Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1205646..1206184 Replicon chromosome
Accession NZ_CP049045
Organism Pseudomonas sp. BIOMIG1BAC

Toxin (Protein)


Gene name relE Uniprot ID A0A6G6ZTT3
Locus tag ATY02_RS05460 Protein ID WP_068575728.1
Coordinates 1205906..1206184 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ATY02_RS05455 Protein ID WP_083236103.1
Coordinates 1205646..1205909 (+) Length 88 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ATY02_RS05440 1201610..1203913 - 2304 WP_068575721.1 TonB-dependent siderophore receptor -
ATY02_RS05445 1204122..1204802 + 681 WP_068575723.1 Fe2+-dependent dioxygenase -
ATY02_RS05450 1204806..1205591 + 786 WP_068575724.1 sel1 repeat family protein -
ATY02_RS05455 1205646..1205909 + 264 WP_083236103.1 ribbon-helix-helix domain-containing protein Antitoxin
ATY02_RS05460 1205906..1206184 + 279 WP_068575728.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ATY02_RS05465 1206262..1207425 - 1164 WP_068575730.1 type III PLP-dependent enzyme -
ATY02_RS05470 1208103..1209260 - 1158 WP_068575732.1 ABC transporter ATP-binding protein -
ATY02_RS05475 1209257..1209925 - 669 WP_068575734.1 ABC transporter permease -
ATY02_RS05480 1209938..1210831 - 894 WP_068575736.1 glycine betaine ABC transporter substrate-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 93 a.a.        Molecular weight: 10787.55 Da        Isoelectric Point: 10.8284

>T150323 WP_068575728.1 NZ_CP049045:1205906-1206184 [Pseudomonas sp. BIOMIG1BAC]
MRQLKWTSKALSDLARLFEFLAQVNRSAAARTVQSLVRAPDALLSNPRLGEQLEEFKPKDVRRLLVGHYEVRYEIQGMVL
SILRIWHVREDR

Download         Length: 279 bp

>T150323 NZ_CP064674:2441139-2441423 [Salmonella sp. SJTUF14076]
ATGACTTATAAGCTGGCATTTAACGAATCTGCACTAAAAGAGTGGAAAAAACTGGGTCATACCATACAGGAACAGTTTAA
AAAAAAGCTACGGGAACGACTCGAAAACCCTCGGGTTCCTGCTTCGCAATTACATGGAAGAAAGGATCAGTACAAAATTA
AGCTGCGTGGTGCAGGATACAGACTGGTGTACAGCGTCGAAGATGAAATTATCACGGTAACTGTCATTGGTGTTGGAAAG
CGTGAAAATGATGCCGTCTACAAAATGACACGGCACAGAAGCTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9691.09 Da        Isoelectric Point: 5.0878

>AT150323 WP_083236103.1 NZ_CP049045:1205646-1205909 [Pseudomonas sp. BIOMIG1BAC]
MPATKVLTAHIPLDLADKVDQLASRLERSRAWIVKQALVAWVDQEEERRRLTLEALADVDAGRVVDHQSVLAWAESLSGD
NPLPLPK

Download         Length: 264 bp

>AT150323 NZ_CP064674:2440901-2441149 [Salmonella sp. SJTUF14076]
ATGGCATTTCAAATTTTAACGACTACTGCAGCAAGCATTACAGAACTGAAACGTGACCCAATGGGAACTTTCAATGCCGG
AGATGGCGCTCCAGTTGCCATTCTTAACCGTAATGAACCGGCTTTCTACTGTGTGCCTCCGGCACTTTATGCTCATCTTA
TGGATATTCTTGAGGATGAAGAACTCGGTCGTATTATCGATGAGCGTGCGAATGAACGCGTCATTGAGGTCAACATTGAT
GACTTATAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A6G6ZTT3


Antitoxin

Source ID Structure

References