150298

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4078265..4078652 Replicon chromosome
Accession NZ_CP049017
Organism Xanthomonas theicola strain CFBP 4691

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag G4Q83_RS19080 Protein ID WP_003469322.1
Coordinates 4078518..4078652 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID -
Locus tag G4Q83_RS19075 Protein ID WP_128419193.1
Coordinates 4078265..4078417 (+) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G4Q83_RS19035 4073495..4073665 + 171 Protein_3752 hypothetical protein -
G4Q83_RS19040 4073905..4074231 + 327 WP_128419189.1 metal/formaldehyde-sensitive transcriptional repressor -
G4Q83_RS19045 4074228..4075337 + 1110 WP_128419190.1 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase -
G4Q83_RS19050 4075407..4075979 + 573 WP_128419191.1 S-(hydroxymethyl)glutathione synthase -
G4Q83_RS19055 4076059..4076889 + 831 WP_128419192.1 S-formylglutathione hydrolase -
G4Q83_RS19060 4076938..4077123 - 186 WP_170069131.1 hypothetical protein -
G4Q83_RS19065 4077142..4077452 - 311 Protein_3758 transposase -
G4Q83_RS19070 4077540..4078120 + 581 Protein_3759 arginase family protein -
G4Q83_RS19075 4078265..4078417 + 153 WP_128419193.1 entericidin A/B family lipoprotein Antitoxin
G4Q83_RS19080 4078518..4078652 + 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
G4Q83_RS19085 4078872..4079090 + 219 Protein_3762 DUF4102 domain-containing protein -
G4Q83_RS19090 4079108..4079496 + 389 Protein_3763 IS5 family transposase -
G4Q83_RS19095 4079595..4080407 - 813 WP_128419233.1 cellulase -
G4Q83_RS19100 4080963..4081364 + 402 WP_128419194.1 LysR family transcriptional regulator -
G4Q83_RS19105 4081578..4081862 + 285 WP_158254966.1 hypothetical protein -
G4Q83_RS19110 4082172..4082486 + 315 WP_128419196.1 nuclear transport factor 2 family protein -
G4Q83_RS19115 4082675..4083013 + 339 WP_128419197.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T150298 WP_003469322.1 NZ_CP049017:4078518-4078652 [Xanthomonas theicola]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T150298 NZ_CP064671:c1054667-1054140 [Salmonella sp. SJTUF14152]
ATGATGTTTACAGACTGGCATGAGGCCGCGATAGGGAAAACCCACAATCGAATGAATTTTGATTGTGGGGATGCCGATCT
GAACCAATTCCTGCAACGCCATGCACGACAAAATCATGAGAAAGGGACAACGAAAACCTATGTTGCGCTTGATAATTCGG
ATGTTACACGTATCCACGGCTTTTACTCAGTCAGTCCTGCATCACTGATATATGCACAGGTTCCCGGCGCAATCAGCAAA
GGATTAGGGAGATATGATGTGCCAGTGTTTCGTCTGGGTCGTTTAGCCGTAGACAAATCTATGCAGGGGCAAGGGCTGGG
AGCACAACTTTTGTTATCTGCCGGAAAGCGTTGCATACAGGCGGCTTTGCAGGTCGGTAGCGTAGCCCTGCTTATTGATG
CCAAAAATAAACAGGTCTGCGACTGGTACAAAGGATTTGGCGCAGTACCATTAAACGATCAACCCCTTTCCTTGTTGCTG
TCGTTTAAAACGCTTTATGCTGCTTTATCTGCATCTGGTAGGTTATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5231.19 Da        Isoelectric Point: 7.5954

>AT150298 WP_128419193.1 NZ_CP049017:4078265-4078417 [Xanthomonas theicola]
MKRLLTSMLLTLFCAGMLTGCNTMAGAGKDMQKAGEKVEDKAGDCSDGKC

Download         Length: 153 bp

>AT150298 NZ_CP064671:c1054954-1054664 [Salmonella sp. SJTUF14152]
ATGAAAACCATGCCTCAGATAGCTATAGAATCTAACGAAAGGCTGTCGTTGCGTGTATCGACGGATGCCAAAAAGTTGAT
AGTCCGCGCTGCGGCAATCCAGCAAACCAACCTGACGGATTTTGTGGTCAGTAACGTACTACCTGTCGCACAGAAGATTG
TTGATGCCGCCGAACGGGTATATCTGACGGAGCGCGATACTAAAATGATCATGGAAATTTTAGATAACCCGCCAGCGCCG
AATGAAAAGCTTCTTGCCGCTGCTTTCGCCCTGCCGGACATGAAGAAATGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5


Antitoxin

Source ID Structure

References