Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parE_1-relB/-
Location 1768649..1769121 Replicon chromosome
Accession NZ_CP049017
Organism Xanthomonas theicola strain CFBP 4691

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag G4Q83_RS08100 Protein ID WP_128421893.1
Coordinates 1768840..1769121 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag G4Q83_RS08095 Protein ID WP_128421892.1
Coordinates 1768649..1768840 (+) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G4Q83_RS08070 1764448..1765431 + 984 WP_185817191.1 IS5 family transposase -
G4Q83_RS08075 1765605..1766414 + 810 WP_128421888.1 hypothetical protein -
G4Q83_RS08080 1766414..1766797 + 384 WP_128421889.1 DUF2523 domain-containing protein -
G4Q83_RS08085 1766797..1767984 + 1188 WP_128421890.1 hypothetical protein -
G4Q83_RS08090 1767986..1768636 + 651 WP_128421891.1 conjugal transfer protein -
G4Q83_RS08095 1768649..1768840 + 192 WP_128421892.1 stability determinant Antitoxin
G4Q83_RS08100 1768840..1769121 + 282 WP_128421893.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G4Q83_RS08105 1769165..1769443 - 279 WP_128421894.1 hypothetical protein -
G4Q83_RS08110 1769716..1770147 - 432 Protein_1595 IS200/IS605 family transposase -
G4Q83_RS08115 1770572..1772422 - 1851 WP_128420036.1 monovalent cation:proton antiporter-2 (CPA2) family protein -
G4Q83_RS08120 1772432..1772578 - 147 WP_158255003.1 hypothetical protein -
G4Q83_RS08125 1772734..1773873 - 1140 WP_128420035.1 molybdopterin-synthase adenylyltransferase MoeB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 1760214..1770147 9933
- inside Prophage - - 1729024..1770147 41123


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10605.40 Da        Isoelectric Point: 6.7144

>T150294 WP_128421893.1 NZ_CP049017:1768840-1769121 [Xanthomonas theicola]
MLPILWRESADADLAVIIDYVGQFDLAAAERLWQLLRASVLPLAEHPYLHPQSWRVPGCREIVVTRNYVVLYRVTVAAVE
VVAVVHARREFPV

Download         Length: 282 bp

>T150294 NZ_CP064667:184636-185961 [Salmonella sp. SJTUF14154]
ATGAGCCGGAAACAGCAACGTCTGGTAATTTGGATGAACGGCATCAAAGTCGGGTACTGGGAAAAAAGCAAAGGGGTAGA
CAGCTTAGAATACCTTCCTGAATGGGTTGCTGACGAACAGGGAAGGCCGCTGTCATTGTCCCTTCCTTTTACTCCCGGGA
ACCAGGTCTGGCGTGGAAATGTGGTACGTGACTATTTTGATAATTTACTGCCGGACAGCGAAGGCATACGCAGACGTCTG
GCAATGCGTTACAAGGCCGATAGCCTGGAGCCTTTTGATCTGCTGACGGAGCTGGGAAAAGACTGCGTGGGCGCGATACA
GCTGCTTCATGACGGAGATGAACCCACTGATTTATATTCCGTGAAGTATCACCCGCTTACTGAATCAGAAATTGCGGCAA
CTTTGCGTAATACCACGGAGACATTGCTACCGGGCAGGCCAGAAGATAACGACGACTTACGTTTATCTATTGCCGGTGCT
CAGGAGAAAACAGCCCTACTGTGGCATGAAGATCGGTGGTGTATGCCGGAGGGTAATACACCAACGACGCATATATTCAA
GCTACCGCTCGGACTTGTGGGGAACATGAAAGCCGACATGAGCTCGTCGGTTGAAAATGAATGGCTCTGCTCGGTACTTC
TCGGCCAGTACGGGCTCCCCGTGGCAAGAACGCAGATTGCTCACTTTGAAGATCAGAAAGCGCTGGTGGTAGAACGTTTT
GACCGAAAATGGTCAGGAGACGGACAATGGATCATTCGTTTACCCCAGGAGGATATGTGTCAGGCCCTGGGCGTTTCGCC
ATTACGAAAATATCAGGCGGACGGCGGGCCAGGTATATCGGAAATTATGGAGGTTCTGAGTAATTCAGACCGTGCTGAGC
GTGACAAAGCGCAGTTTTTTATGACGCAGATAATTTTCTGGATGATGGCCGCAACAGATGGCCACGCTAAAAATTTCAGT
ATTTCTATTGGGCCACAGGGACGTTATCACCTTACACCAAACTATGATGTGTTGTCGGCATGGCCGGTGATCGGTCATGG
GAACAATCAGATATCCTGGCAGAAGTGCAAACTGGCGATGGCCGTACGTGGCAGTAGCAACTATTACCAGATATATCGAA
TACAACGACGCCACTGGATCAGGCATGGTGAGATAACCGGCCTGAGTAAACAGCAGACAGAGGCGATGATAGAGGAAATC
ATCGCCAGAACCCCGGGTGTCATTGAACGTGTTAGCGGGCTTCTTCCGGACCAGTTCCCCCAGCAGCTTGCGGAAAGTAT
TTTTGATGGAATGAGGCAGCAATGCAGGCGCCTGGCTGAGAAATGA

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7030.82 Da        Isoelectric Point: 5.0053

>AT150294 WP_128421892.1 NZ_CP049017:1768649-1768840 [Xanthomonas theicola]
MNNVRSPLAYEFETADAEANYDAWLRTKVAASVADSSPLIPHDEVERRMAERLTALKAKHSAD

Download         Length: 192 bp

>AT150294 NZ_CP064667:184338-184631 [Salmonella sp. SJTUF14154]
ATCAATAATGATTACCCGTTAAACACGCTCAACCAGCTGCGTCCCTTGCTCATTGGTTTTCGCAAGGCGAATGGCCTGAC
GCAAAAAGACCTGTCCGAAAGGTTAGGCGTCACTCAACAGACATACTCACGTCTGGAAGCCAACCCTGCCAGTGCGAGCA
TTGAACGGCTATTCAAGGTGTTTTCCATCCTGGGCGTAAAAATCAGCTTCTCCTCGGCAACCACCTCTTCAGAGAGGAAG
CAGACGGAAGAAATGCTTAAATCAAACTCACCTGCACGACAGGAGGATTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References