Detailed information of TA system TA150293

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN-MazE
• Location: 1351086..1351719
• Replicon: chromosome
• Accession: NZ_CP049017
• Organism: Xanthomonas theicola strain CFBP 4691

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: G4Q83_RS06135
• Protein ID: WP_128421518.1
• Coordinates: 1351306..1351719 (+)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: G4Q83_RS06130
• Protein ID: WP_128421519.1
• Coordinates: 1351086..1351319 (+)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G4Q83_RS06120	1349650..1350876	+	1227	WP_128421523.1	hypothetical protein	-
G4Q83_RS06125	1350931..1351008	-	78	Protein_1206	DUF4400 domain-containing protein	-
G4Q83_RS06130	1351086..1351319	+	234	WP_128421519.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
G4Q83_RS06135	1351306..1351719	+	414	WP_128421518.1	PIN domain-containing protein	Toxin
G4Q83_RS06140	1351786..1352265	+	480	Protein_1209	DDE-type integrase/transposase/recombinase	-
G4Q83_RS06145	1352320..1353258	-	939	WP_128422000.1	IS1595 family transposase	-
G4Q83_RS06150	1353573..1354544	-	972	Protein_1211	IS5 family transposase	-
G4Q83_RS06155	1354658..1355062	+	405	WP_128420293.1	hypothetical protein	-
G4Q83_RS06160	1355186..1356235	-	1050	WP_128420294.1	glycosyltransferase family 9 protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1340830..1353258	12428

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (8-119)

Antitoxin

• SpoVT-AbrB domain (5-40)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 15343.74 Da
• Isoelectric Point: 5.9795

>T150293 WP_128421518.1 NZ_CP049017:1351306-1351719 [Xanthomonas theicola]
MAGGSAKIFLDSNMVLYLLSEDSAKADDAEKLLQRRPIISVQVLNEVTHVCVRKLKMGWGEVGQFLALVREFCKVVPLTV
DVHDRARQLAERHQLSFYDACIIAAAAIEGCQTLYTEDMHHGLIIEESLSIRNPFNT

Nucleotide

• Length: 414 bp

>T150293 NZ_CP064666:4552633-4552944 [Salmonella sp. SJTUF14154]
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCCCTCACTGAGTTGCT
GAATGTTCTGGAGAAAAAAACATTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGTACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTTTCCCATGCCGAATATGACAAACTGACCGCATATTATCGGGGTAATGAAGAATGA

Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 8675.97 Da
• Isoelectric Point: 8.8317

>AT150293 WP_128421519.1 NZ_CP049017:1351086-1351319 [Xanthomonas theicola]
MQVAKWGNSLAVRLPASLVEALELREGDDIEIVVDEPRLFAVRKKPGSEALLERLRAFRGKLPADFRFNREEANGRG

Nucleotide

• Length: 234 bp

>AT150293 NZ_CP064666:4552941-4553387 [Salmonella sp. SJTUF14154]
ATGAGAACTCATCGTCAGATGGATGCAACCAGCGCAAAAAAGATCGTTGATACCTTCAGCGATGCGGTAAAAAGCGTCCC
ACTGATGGGGGAAGACCGAAATGACAATGAGTATCGCAGGGCACTAGCGCTAGTGGAGTTTCTGGTCGACCACGACGATC
TTGAAAACCCACTATTTGAATTGCTCTGTGCCCGAATCAGTGAATACGAAAAACATGCGCCGGAATTCAAAGCACTCAAC
CAACACCTGGAGAAAACGCCCCCTGGCGTTTCAGTATTGCGAACGCTCATGGATCAATACGGTCTCAAAGCAGCAGATCT
TGCCAACGAACTTGGTTCTAAATCGAACGTCAGCAACATCTTAAATGGCCGCAGAGCACTAACGGTTAATCATATTAAAG
CGCTTACACAACGCTTTAAACTACCAGCGGATGCCTTCATCGAGTAG