Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 688478..688749 Replicon chromosome
Accession NZ_CP048934
Organism Escherichia coli strain 190693

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 688516..688619 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 688478..688749 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G5C00_RS03380 685635..687074 + 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
G5C00_RS03385 687192..687428 + 237 WP_001295499.1 DUF1480 family protein -
G5C00_RS03390 687533..687724 + 192 WP_001296140.1 YebW family protein -
G5C00_RS03395 687725..688381 - 657 WP_163510366.1 protein-serine/threonine phosphatase -
- 688478..688749 + 272 - - Antitoxin
- 688516..688619 - 104 - - Toxin
G5C00_RS03400 688777..689118 - 342 WP_000976472.1 YebY family protein -
G5C00_RS03405 689131..690003 - 873 WP_001551232.1 copper homeostasis membrane protein CopD -
G5C00_RS03410 690007..690381 - 375 WP_000168747.1 CopC domain-containing protein YobA -
G5C00_RS03415 690520..690750 + 231 WP_000916763.1 DNA polymerase III subunit theta -
G5C00_RS03420 690852..691508 + 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
G5C00_RS03425 691532..692194 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 672638..712534 39896


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T150249 NZ_CP048934:c688619-688516 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT150249 NZ_CP048934:688478-688749 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References