Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2015860..2016005 Replicon chromosome
Accession NZ_CP048933
Organism Klebsiella pneumoniae strain KP18-2079

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2015896..2015998 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2015860..2016005 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G5B45_RS10045 2010990..2013050 + 2061 WP_004151449.1 oligopeptidase B -
G5B45_RS10050 2013054..2013713 - 660 WP_002911407.1 exodeoxyribonuclease X -
G5B45_RS10055 2013792..2014022 - 231 WP_002911406.1 DNA polymerase III subunit theta -
G5B45_RS10060 2014135..2014509 + 375 WP_004151448.1 CopC domain-containing protein YobA -
G5B45_RS10065 2014513..2015382 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
G5B45_RS10070 2015399..2015737 + 339 WP_002911404.1 YebY family protein -
- 2015860..2016005 - 146 - - Antitoxin
- 2015896..2015998 + 103 - - Toxin
G5B45_RS10075 2016373..2016516 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
G5B45_RS10080 2016621..2017589 - 969 WP_004151446.1 VirK/YbjX family protein -
G5B45_RS10085 2017746..2018399 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
G5B45_RS10090 2018396..2018587 - 192 WP_002911395.1 YebW family protein -
G5B45_RS10095 2018685..2018924 - 240 WP_002911393.1 YebV family protein -
G5B45_RS10100 2019040..2020473 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T150233 NZ_CP048933:2015896-2015998 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT150233 NZ_CP048933:c2016005-2015860 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References