Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1994059..1994330 Replicon chromosome
Accession NZ_CP048915
Organism Escherichia coli strain E2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1994189..1994292 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1994059..1994330 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G5S48_RS09535 1990614..1991276 - 663 WP_000944256.1 exodeoxyribonuclease X -
G5S48_RS09540 1991300..1991956 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
G5S48_RS09545 1992058..1992288 - 231 WP_000916763.1 DNA polymerase III subunit theta -
G5S48_RS09550 1992427..1992801 + 375 WP_000204699.1 CopC domain-containing protein YobA -
G5S48_RS09555 1992805..1993677 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
G5S48_RS09560 1993690..1994031 + 342 WP_000976492.1 YebY family protein -
- 1994059..1994330 - 272 - - Antitoxin
- 1994189..1994292 + 104 - - Toxin
G5S48_RS09565 1994427..1995083 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
G5S48_RS09570 1995084..1995275 - 192 WP_001296140.1 YebW family protein -
G5S48_RS09575 1995380..1995616 - 237 WP_001295499.1 YebV family protein -
G5S48_RS09580 1995734..1997173 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1951146..2010168 59022


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T150178 NZ_CP048915:1994189-1994292 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT150178 NZ_CP048915:c1994330-1994059 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References