Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-MazE
Location 66027..66628 Replicon plasmid pC
Accession NZ_CP048881
Organism Spartinivicinus ruber strain S2-4-1H

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag G4Y78_RS30495 Protein ID WP_163836992.1
Coordinates 66027..66377 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag G4Y78_RS30500 Protein ID WP_163836993.1
Coordinates 66371..66628 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G4Y78_RS30475 62202..62816 + 615 WP_163836988.1 hypothetical protein -
G4Y78_RS30480 62818..63168 + 351 WP_163836989.1 hypothetical protein -
G4Y78_RS30485 63297..64853 - 1557 WP_163836990.1 Fic family protein -
G4Y78_RS30490 65370..66017 - 648 WP_163836991.1 hypothetical protein -
G4Y78_RS30495 66027..66377 - 351 WP_163836992.1 type II toxin-antitoxin system ChpB family toxin Toxin
G4Y78_RS30500 66371..66628 - 258 WP_163836993.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
G4Y78_RS30505 66905..67756 - 852 WP_163836994.1 hypothetical protein -
G4Y78_RS30510 68140..68733 + 594 WP_163836995.1 tyrosine-type recombinase/integrase -
G4Y78_RS30515 68768..70504 - 1737 WP_163836996.1 methyl-accepting chemotaxis protein -
G4Y78_RS30520 70641..70784 + 144 WP_163836997.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..82464 82464


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

Antitoxin PemI-like

(1-85)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12502.42 Da        Isoelectric Point: 9.6549

>T150145 WP_163836992.1 NZ_CP048881:c66377-66027 [Spartinivicinus ruber]
MVKRNQFERGDIVRVSLNPVVGNEVQGDFRPCLVLSPSSYNRLGTAFVAPITQGGNYSRYQGFAIPLMGAGTETQGVILV
NGARMLNLAARKAKKVETAPDDIVQEALARLAAILE

Download         Length: 351 bp

>T150145 NZ_CP064395:c4795487-4795077 [Pseudomonas aeruginosa]
ATGCTCAAGTTCATGCTTGACACCAACATCTGCATCTTCACCATCAAAAACCGCCCGCAAGAGGTGCGCGAGGCGTTCCT
GCGCCACCACGACCAGATGTGCATCAGCACCGTGACGCTGATGGAGCTGATCTACGGCGCAGAGAAGTCCTCGAACCCCT
CGCGCAATCTTGCAGACGTGGAAGGCTTCGCTGCTCGTCTGGAGGTGCTCAAGTACGACCAGGAAGCTGCCGCCCACACC
GGCCAGCTCCGCGCTGAACTGGCCCGCCTCGGCAAGCAAATCGGCCCCTATGACCAGATGATCGCCGGGCACGCCCGCTC
TCAGGGCCTGATCGTGGTCACCAATAACCGCCGCGAGTTCGACCGCGTACCCGGCTTGAGAGTTGAGGATTGGGTCACCC
CAATCGTGTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9285.47 Da        Isoelectric Point: 4.5203

>AT150145 WP_163836993.1 NZ_CP048881:c66628-66371 [Spartinivicinus ruber]
MRTTIRKIGNSSGAIIPAALLKKYNLTEGDAINIEENGSNIVISPVTKRPKYKLDELLAQCDSNAPVSEELSDWDNSPAV
GNEIW

Download         Length: 258 bp

>AT150145 NZ_CP064395:c4795717-4795487 [Pseudomonas aeruginosa]
GTGGAACAAGGTTCTGTTTTTCAGAGCAATCGTAGCCAGGCCGTAAGACTGCCCAAGGCCGTCGCGCTTCCTGATGACGT
TAAGCGTGTGGATGTGGTCGCTGTGGGGCGCGCCAGAATCATCACGCCTGCCGGCGAGTCTTGGGATAGCTGGTTCGATG
GCGAGGGCGTTACTGCCGACTTTATGGCAGAGCGTGAACAGCCTGCCGATCAGGAGCGCGAGACTTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References