Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 6040563..6041068 Replicon chromosome
Accession NZ_CP048878
Organism Spartinivicinus ruber strain S2-4-1H

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag G4Y78_RS27275 Protein ID WP_163836100.1
Coordinates 6040563..6040817 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag G4Y78_RS27280 Protein ID WP_163836097.1
Coordinates 6040814..6041068 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G4Y78_RS27230 6035687..6036100 + 414 WP_163836092.1 PIN domain nuclease -
G4Y78_RS27235 6036056..6036457 - 402 WP_163836093.1 type II toxin-antitoxin system VapC family toxin -
G4Y78_RS27240 6036447..6036713 - 267 WP_163836094.1 hypothetical protein -
G4Y78_RS27245 6036895..6037218 + 324 WP_163836095.1 type II toxin-antitoxin system HicB family antitoxin -
G4Y78_RS27250 6037328..6037582 - 255 WP_163836096.1 Txe/YoeB family addiction module toxin -
G4Y78_RS27255 6037579..6037833 - 255 WP_163836097.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
G4Y78_RS27260 6038076..6039356 - 1281 WP_163836066.1 ISL3 family transposase -
G4Y78_RS27265 6039488..6039868 - 381 WP_163836098.1 type II toxin-antitoxin system VapC family toxin -
G4Y78_RS27270 6039858..6040124 - 267 WP_163836099.1 hypothetical protein -
G4Y78_RS27275 6040563..6040817 - 255 WP_163836100.1 Txe/YoeB family addiction module toxin Toxin
G4Y78_RS27280 6040814..6041068 - 255 WP_163836097.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
G4Y78_RS27285 6041179..6041835 + 657 WP_163836101.1 type II toxin-antitoxin system HicB family antitoxin -
G4Y78_RS27290 6041863..6042045 - 183 WP_163836102.1 hypothetical protein -
G4Y78_RS27295 6042075..6042488 - 414 WP_163836103.1 type II toxin-antitoxin system VapC family toxin -
G4Y78_RS27300 6042488..6042721 - 234 WP_163836104.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
G4Y78_RS27305 6042835..6043074 + 240 WP_163836105.1 hypothetical protein -
G4Y78_RS27310 6043091..6044371 + 1281 WP_163836066.1 ISL3 family transposase -
G4Y78_RS27315 6044514..6045359 + 846 WP_163836088.1 transporter substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - pilM / pilJ / pilH / pilG / pilU / pilT 5758046..6217034 458988


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10291.79 Da        Isoelectric Point: 8.8305

>T150137 WP_163836100.1 NZ_CP048878:c6040817-6040563 [Spartinivicinus ruber]
MILSWAELAWEDYLYWQQTDKKTLKRINTLIKDIKHQPFDGLGDPEPLKHNWSGYWSRRIDREHRLVYKVTDTAIIVVQC
RYHY

Download         Length: 255 bp

>T150137 NZ_CP064393:c5547646-5547356 [Pseudomonas aeruginosa]
ATGACCGAGCAAATTTATGATTATGACCCCGCGCAAGCGCTGGACAGCCCGGAGGCCATGGCTCTGTTCATCGCAGACGC
TTTGGATACTGGAGACACCGCCTATATCGCTAAGGCTATGGGAGTCGTGGCCCGCGCCAAGGGGATGACGGAGTTGGCCA
AGGAAACGGGTTTGGCCAGGGAGCAGCTTTACAAATCGTTTAGTGAGCGCGGGAACCCTACATTGAAAACCATGCTGGCA
GTAATGCGAGCTCTGGGAGTTGATCTGACCGCCCGCCCGCATGCTCAGTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9362.53 Da        Isoelectric Point: 4.7672

>AT150137 WP_163836097.1 NZ_CP048878:c6041068-6040814 [Spartinivicinus ruber]
MDTISYSAFRSKLAGTLDKVNDDHTPVLITRQNGKPAVLMSLEDFKSYEATAYLMASQRNAERLNQAIAQVEDGKTVERG
LIEE

Download         Length: 255 bp

>AT150137 NZ_CP064393:c5547942-5547643 [Pseudomonas aeruginosa]
ATGGTCGAAGTCAAACAAACCGCCACTTTCATGGCATGGGAAAGCAAGCTAAAGGATCGGCGGGCAAAGGCCGTGATCGC
CGCCCGTATCTTCCGATTGGCGAATGGACTACCCGGCGATGTGTCACCAGTCGGCCAGGGTGTGAGCGAGTTGAGGATTC
ACTATGGCCCAGGCTATCGGGTGTACTTCCAGCAGCGCGGGACGGAAATCGTCATCCTGCTATGTGGTGGAGACAAGAGC
AGCCAGGCCAGGGATATAGAAATGGCGAAACGCCTGGCAAATGAGTGGAGGCCGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References