Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 5928649..5929285 Replicon chromosome
Accession NZ_CP048878
Organism Spartinivicinus ruber strain S2-4-1H

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag G4Y78_RS26685 Protein ID WP_163836001.1
Coordinates 5928869..5929285 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag G4Y78_RS26680 Protein ID WP_163836000.1
Coordinates 5928649..5928882 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G4Y78_RS26665 5925068..5925556 - 489 WP_163835997.1 pilin -
G4Y78_RS26670 5926581..5927552 + 972 WP_163835998.1 hypothetical protein -
G4Y78_RS26675 5927879..5928562 + 684 WP_163835999.1 hypothetical protein -
G4Y78_RS26680 5928649..5928882 + 234 WP_163836000.1 DNA-binding protein Antitoxin
G4Y78_RS26685 5928869..5929285 + 417 WP_163836001.1 type II toxin-antitoxin system VapC family toxin Toxin
G4Y78_RS26690 5929291..5929545 - 255 WP_163836002.1 hypothetical protein -
G4Y78_RS26695 5929914..5930369 + 456 WP_163836003.1 hypothetical protein -
G4Y78_RS26700 5930664..5932046 + 1383 WP_163836004.1 HDOD domain-containing protein -
G4Y78_RS26705 5932067..5932591 - 525 WP_163836005.1 hypothetical protein -
G4Y78_RS26710 5932725..5933108 - 384 WP_163836006.1 helicase -
G4Y78_RS26715 5933251..5933532 - 282 WP_163836007.1 HU family DNA-binding protein -
G4Y78_RS26720 5934003..5934170 - 168 WP_163836008.1 rubredoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - pilM / pilJ / pilH / pilG / pilU / pilT 5758046..6217034 458988


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-129)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15825.06 Da        Isoelectric Point: 9.8487

>T150133 WP_163836001.1 NZ_CP048878:5928869-5929285 [Spartinivicinus ruber]
MYLVDTNVISEVRKVNKANPGVVDFFKKTEREDARIYLSVITIGELRRGVEKIRHRGDIKQANQLEKWLNNIIVNFSNNI
LEFSETEANVWGRLRVPHHENAIDKQIAATALTYGLTLVTRNTNDFTQTGVKLLNPFT

Download         Length: 417 bp

>T150133 NZ_CP064393:1907611-1908198 [Pseudomonas aeruginosa]
ATGTCGAGGAGGGCGCCCATGTTCAAGCCGCTACCGATCACCCTGCAGCGCGGAGCCTTGCGTCTCGAGCCGTTGGTGGA
AGCGGACATTCCCGAGCTGGTGAGCCTCGCCGAAGCCAACCGCGAGGCGCTGCAGTACATGGACGGACCGACGCGGCCGG
ACTGGTACCGCCAGAGCCTCGCCGAGCAGCGCGAGGGCAGGGCGTTGCCGCTCGCCGTCCGCCTCGGCGTGCAACTGGTC
GGGACCACGCGCTTCGCCGAGTTCCTTCCCGCCTTGCCGGCCTGCGAGATCGGCTGGACCTGGCTCGACCAGGCCCAGCA
CGGCAGCGGCCTGAACCGCATGATCAAGTACCTGATGCTCAAGCATGCCTTCGACAACCTGCGCATGGTCCGCGTGCAGC
TCAGCACGGCGGCGAGCAACCTGCGCGCCCAGGGCGCCATCGACAAGCTCGGCGCGCAGCGCGAGGGCGTGCTGCGCAAC
CACCGGCGGCTGGCCGGCGGGCGGCTAGACGACACCTTCGTCTACAGCATCACCGACCACGAATGGCCGCAGGTCAAGGC
GGCGCTGGAAGCCAGCTTCACCGGCTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8543.70 Da        Isoelectric Point: 5.0878

>AT150133 WP_163836000.1 NZ_CP048878:5928649-5928882 [Spartinivicinus ruber]
MANLVVRNIDDDVVKALKALAGKHGISAEAEHRRILEAALLRPKKKSFVEALQTIPNVGLDSDFERVQDDQETDVFS

Download         Length: 234 bp

>AT150133 NZ_CP064393:1908265-1909119 [Pseudomonas aeruginosa]
GTGCCGGACGAGACGAGCGGAGAACACACGCATTTCTGGCGCGCCGCCGAACTGGGCGGCGTCGAACTGCTGCACGCGCG
CTATGTGGAGCAGCGCTTCGCGCCGCACGTGCACAGCAGCTTCGCCCTGGTCATCATCGAGCAGGGCGCGCAGCGCTTCC
GCCATCGTGGCGGCGAGCACCTGGCCCCGCTGGGCAGCATGGTGCTGATCAACCCCGACGAAGTGCACACCGGCTCCAAG
GCCCATGATGCCGGTTGGCTCTATCGCGGCTACTACCCGGAAATGGAACAGATCGACGGGATTCTCGACGAGCTGGAAAT
CCATCATGGCGGTGTGCCGCGCTTCGCCGACAGCGTGATCCACGACCAGCCCCTGGCACGCGCCTTCGTCCACTTGCACC
GCCTGCTGGCCGAGCATGCCGGCAGCCTGGAAACCCAGACCCGCTGGCGCGAGACGGTGCTCGCCCTGTTCCGTCGCCAC
GCCCGCCTGCCAGAAGCGCCGAAGGCCGGGCAGGAGCCGTTGGCGGTGGCCCGTGCCCGCGAACTGCTGGCGGCGCGGTT
GCTCGATCCGCCTTCGCTGGAGGAACTGGCGGCGGCGGTCAATCTGTCCCCGTTCCATTTTGCCCGGGTCTTCCGTCGCG
CCACCGGCATGCCGCCCCACGCCTGGCTCAGGCAGCGCCGCCTGGAGCAGGCCAGGGCACTGCTCAAGAGCGGCCGGGCG
CCGCTGGAGGTGGCCCTGGAGCTGGGCTTCGCCGACCAGAGCCACCTCGGTCGCCAGTTCAAGCAGGCCTACGGCGTGGC
ACCGGGTGAATACCGCTCGGCCTGCGCGCGCTCATCCTTGACGATCTACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References