Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PhRel2-ATphRel2/DUF4065(antitoxin)
Location 1193580..1195039 Replicon chromosome
Accession NZ_CP048852
Organism Bacillus tequilensis strain EA-CB0015

Toxin (Protein)


Gene name phRel2 Uniprot ID -
Locus tag G4P54_RS06315 Protein ID WP_167872121.1
Coordinates 1193580..1194287 (+) Length 236 a.a.

Antitoxin (Protein)


Gene name ATphRel2 Uniprot ID -
Locus tag G4P54_RS06320 Protein ID WP_167872122.1
Coordinates 1194290..1195039 (+) Length 250 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G4P54_RS06300 1190418..1190717 - 300 WP_114168520.1 hypothetical protein -
G4P54_RS06305 1190771..1191079 - 309 WP_100740753.1 hypothetical protein -
G4P54_RS06310 1191100..1192971 - 1872 WP_167872120.1 EndoU domain-containing protein -
G4P54_RS06315 1193580..1194287 + 708 WP_167872121.1 hypothetical protein Toxin
G4P54_RS06320 1194290..1195039 + 750 WP_167872122.1 DUF4065 domain-containing protein Antitoxin
G4P54_RS06325 1196864..1197235 + 372 WP_167872123.1 YrdB family protein -
G4P54_RS06330 1197484..1198050 + 567 WP_167872124.1 cysteine hydrolase -
G4P54_RS06335 1198344..1198543 - 200 Protein_1176 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RelA/SpoT

(99-209)

Antitoxin

Antitoxin SocA-like, Panacea domain

(113-224)


Sequences

Toxin        


Download         Length: 236 a.a.        Molecular weight: 28356.32 Da        Isoelectric Point: 6.6513

>T150115 WP_167872121.1 NZ_CP048852:1193580-1194287 [Bacillus tequilensis]
VINCTCEMESFCDTFYELIIDINNAHKEISTEFHLEKKDDLINLKRKQINHVTHINEENTFSVDSLFLQLISNYREELLL
YSAYTDLENKYKELILRLRTKETTSIVNKLKYYLVGKKEEGKIPINKCLNDLLGFRIHPTFFDHNKNCFQKTCQQLKQIY
NNRIDFMDSSKGNYKAFHIYLYGEEWKYFPWEIQIWCLKDRTQNDLSHKDHKQEHKKWAEIYKNSTEIELEMEGV

Download         Length: 708 bp

>T150115 NZ_CP064389:c2493025-2492702 [Staphylococcus aureus]
ATGAATTGGGAAATTAAAGATTTAATGTGTGACATTGAAGTGATAAAACAAAAAATTAATGATGTAGCTACCAAACATGC
TTGGTTTGTTGAAGATAGATTTGTAAAAAATGAATTAGAAACAAAACGGGAACATATTAATTTTTCTGCTAGCTATTTAG
AACATCGTATACAAAATGAACATACAGTTGAGTTATTACAGGTTTATTTAAAAGAGTTCGATGAACTTATACAAAAATTT
CATGAAATAGAAAAAGCGTCATCTGATGTAAGTTTGGCGACAGAATCAGATGACGCAAAGAATTCAATAAAAGTAGCAGA
GTAA

Antitoxin


Download         Length: 250 a.a.        Molecular weight: 29013.95 Da        Isoelectric Point: 5.7647

>AT150115 WP_167872122.1 NZ_CP048852:1194290-1195039 [Bacillus tequilensis]
MAFHFIAIVSDFSGGRRYGWHYSSEDQLDKEYIKLFITRIKKECGHVQFGIHKLTTDDISWDSVVQMDSFFDDVIITNRI
DDFIEVVSNDQQLSAYDVAKFVLAIYPVSHLKLQKLLYYIYSEFLLRTGSKLFKDPIVAFKYGPVVEDIFHRYRIHGSSQ
IDYKEDETFLLRTQEVAYTPSLIKIWTSEYGTAALQCIKDTLLKYGELDAFHLVDKTHQEGGPWARAYKPGQNCEITDDL
IIQYHQYAT

Download         Length: 750 bp

>AT150115 NZ_CP064389:c2493237-2493028 [Staphylococcus aureus]
ATGAATAATGAACAAAAAGAAGTAATAGAACACTTGGTTTATCAACTTGAGTTAAGTGTCATGAATAATTTGGAAAGTTA
CGAACACACAGAATATGTTAATGGTATTGAAGTGGTTTCAGAGATCAGTCGTGAAAAGCACTTAGAATTGATAATGAAAT
GGTGCGCACAAGAATTAAAGAATAATTTTCAATTAGAGAAAGGAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References