Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1467926..1469439 Replicon chromosome
Accession NZ_CP048836
Organism Azoarcus sp. M9-3-2

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag G3580_RS06785 Protein ID WP_173764543.1
Coordinates 1467926..1468843 (-) Length 306 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag G3580_RS06790 Protein ID WP_173764544.1
Coordinates 1468840..1469439 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G3580_RS06765 1463322..1463729 + 408 WP_173764539.1 hypothetical protein -
G3580_RS06770 1463880..1465055 - 1176 WP_173764540.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
G3580_RS06775 1465434..1467230 + 1797 WP_173764541.1 ATP-binding cassette domain-containing protein -
G3580_RS06780 1467478..1467630 - 153 WP_173764542.1 hypothetical protein -
G3580_RS06785 1467926..1468843 - 918 WP_173764543.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
G3580_RS06790 1468840..1469439 - 600 WP_173764544.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
G3580_RS06800 1470042..1470713 - 672 WP_173764545.1 HAD-IA family hydrolase -
G3580_RS06805 1470703..1471398 - 696 WP_173764546.1 bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG -
G3580_RS06810 1471490..1472206 - 717 WP_173764547.1 OmpA family protein -
G3580_RS06815 1472276..1473592 - 1317 WP_173764548.1 TRZ/ATZ family hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(36-267)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-53)


Sequences

Toxin        


Download         Length: 306 a.a.        Molecular weight: 33901.33 Da        Isoelectric Point: 5.4184

>T150110 WP_173764543.1 NZ_CP048836:c1468843-1467926 [Azoarcus sp. M9-3-2]
MSQRNRAASVRARLLNHARESGQDFNLVLTRYALERLLYRLSISAHAGQFLLKGALLFDLWFDIPHRPTRDADFLGFGQA
DLPQLETVFEEVSAIEADDGVDFRPDTVKADEIRKEANYAGIRVTLLALIDGARVSIQLDIGFGDAVTPGPEEVDYPILL
SGFDAPRLRVYPRDTVVAEKLEALTALGIANSRLKDYFDLWILAGHTPFDGDTLRRAIQATFERRRTPFPSHAQPFGLTD
EFANDAQKVQQWRGFLKRNALDALELDTVVAQLRDFLAPALTAASRGTTYPAHWPPGGPWTASGA

Download         Length: 918 bp

>T150110 NZ_CP064389:749258-749509 [Staphylococcus aureus]
ATGAATAATCGCGAACAAATTGAACAATCAGTTATAAGTGCTAGTGCGTATAACGGTAATGACACAGAGGGATTACTAAA
AGAGATTGAGGACGTTTATAAGAAAGCGCAAGCGTTTGATGAAATACTTGAGGGAATGACAAATGCTATTCAACATTCAG
TTAAAGAAGGTGTTGAACTTGATGAAGCAGTAGGGATTATGGCAGGTCAAGTTGTCTATAAATATGAGGAGGAACAGGAA
AATGAGCATTAG

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22260.05 Da        Isoelectric Point: 10.3621

>AT150110 WP_173764544.1 NZ_CP048836:c1469439-1468840 [Azoarcus sp. M9-3-2]
MESSHKRILELAANHGLLRPRDLTAHGLPRVALTRLVRQGKLQRIGYGLYALPERASTEHGTVAEVSRKHPQAIICLLSA
LQLHGITTQAPFEVWVAVANKARAPKMDYPPLRVVRFSGDALTEGIDTVTIDGVPVRVTNVARTVADCFKFRHKIGLDVA
MEALTEAWLAKRIRMDDLWKYAKLCRVANVMRPYMDSLT

Download         Length: 600 bp

>AT150110 NZ_CP064389:749499-749681 [Staphylococcus aureus]
ATGAGCATTAGTGTAGGAGACAAGGTTTTTAATCCAGAAACAAATTCAACTTTAGAAATTGTACAACTTGTTGGCGATAT
TAGAGACACGCATTACAAGTTATCTGACGGATCTATTATTAGTCTTATAGACTTTGTTGTTAAACCAATTCATTTAATCA
AGGAGGAGCAGGAAAATGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References