Detailed information of TA system TA150106

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE(toxin)
• Location: 5817908..5818448
• Replicon: chromosome
• Accession: NZ_CP048833
• Organism: Pseudomonas multiresinivorans strain populi

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: G4G71_RS26550
• Protein ID: WP_169941528.1
• Coordinates: 5817908..5818210 (-)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: G4G71_RS26555
• Protein ID: WP_169941530.1
• Coordinates: 5818191..5818448 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G4G71_RS26540	5813779..5814975	-	1197	WP_169941524.1	EAL domain-containing protein	-
G4G71_RS26545	5814954..5817800	-	2847	WP_169941526.1	response regulator	-
G4G71_RS26550	5817908..5818210	-	303	WP_169941528.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
G4G71_RS26555	5818191..5818448	-	258	WP_169941530.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
G4G71_RS26560	5818520..5820562	-	2043	WP_169941532.1	exodeoxyribonuclease V subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (14-90)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 11506.44 Da
• Isoelectric Point: 10.9380

>T150106 WP_169941528.1 NZ_CP048833:c5818210-5817908 [Pseudomonas multiresinivorans]
MSFASSDPQYRLAFNTSALKEWKKLKGPLKAQFIRKLDERLRNPHVPSARLHGAANRYKIKLASMGYRLVYEVFDDQVVV
LVIAVGKRERGDVYKAAQKR

Nucleotide

• Length: 303 bp

>T150106 NZ_CP064389:330456-330722 [Staphylococcus aureus]
ATGGCTAGGTTAAATATTACGTTTTCGCCTCAAGCCTTTGAAGATTATAAGTATTTTCAGCAGAACGATAAAAAAATGGT
GAAGAAGATTAATGAGTTACTTAAAAGTATTGACAGAAATGGTGCATTGGAAGGTATAGGTAAGCCTGAAAAGTTAAAAT
CGAATCTGACTGGGTATTATAGTAGACGTATCAATCACGAACATAGATTGGTTTATACAGTAGATGACAATCATATAAAA
ATAGCATCATGTAAATACCATTATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9551.97 Da
• Isoelectric Point: 4.3757

>AT150106 WP_169941530.1 NZ_CP048833:c5818448-5818191 [Pseudomonas multiresinivorans]
MPHSMLADVTASITELKKDPMGTVAAGMGHAVAILNRNEPVFYAVPADEYERMMELLDDLQLGRIAEQRKDEPRVEVTLD
ELRQL

Nucleotide

• Length: 258 bp

>AT150106 NZ_CP064389:330205-330456 [Staphylococcus aureus]
ATGATTATTAAAAATTATTCATACGCTCGACAGAATTTAAAGGCACTTATGACAAAAGTAAATGATGATAGTGATATGGT
AACTGTAACATCTACTGATGATAAAAACGTAGTAATCATGTCAGAATCAGATTATAACTCCATGATGGAAACACTTTACC
TCCAACAGAACCCAAATAATGCTGAACACTTAGCTCAATCAATTGCAGATCTAGAACGTGGGAAAACTATAACGAAAGAT
ATAGATGTATAA