Detailed information of TA system TA150105

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 5527515..5528149
• Replicon: chromosome
• Accession: NZ_CP048833
• Organism: Pseudomonas multiresinivorans strain populi

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: G4G71_RS25305
• Protein ID: WP_169941105.1
• Coordinates: 5527745..5528149 (+)
• Length: 135 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: G4G71_RS25300
• Protein ID: WP_169941103.1
• Coordinates: 5527515..5527745 (+)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G4G71_RS25285	5524063..5524602	-	540	WP_045209899.1	YaeQ family protein	-
G4G71_RS25290	5524664..5525842	-	1179	WP_169941099.1	GGDEF domain-containing protein	-
G4G71_RS25295	5526100..5527299	+	1200	WP_169941101.1	CoA transferase	-
G4G71_RS25300	5527515..5527745	+	231	WP_169941103.1	antitoxin	Antitoxin
G4G71_RS25305	5527745..5528149	+	405	WP_169941105.1	tRNA(fMet)-specific endonuclease VapC	Toxin
G4G71_RS25310	5528192..5528878	-	687	WP_169941107.1	GntR family transcriptional regulator	-
G4G71_RS25315	5528951..5529685	-	735	WP_024765199.1	SDR family oxidoreductase	-
G4G71_RS25320	5529999..5531027	+	1029	WP_169941108.1	ABC transporter substrate-binding protein	-
G4G71_RS25325	5531126..5532202	+	1077	WP_169941110.1	phosphotransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-124)

Antitoxin

• SpoVT-AbrB domain (7-52)

Sequences

Toxin

Protein

• Length: 135 a.a.
• Molecular weight: 14846.14 Da
• Isoelectric Point: 6.7127

>T150105 WP_169941105.1 NZ_CP048833:5527745-5528149 [Pseudomonas multiresinivorans]
MLKYLLDTNICIFTIKNKPEAVREAFNRHYGQLCISSITLMELIYGAEKSSAPEANLAVVEGFAARLEVLPYDTDAAAHT
GQLRAELAKVGKPIGPYDQMIAGHARSLGLIVVTNNLREFERVPGLRLEDWTKS

Nucleotide

• Length: 405 bp

>T150105 NZ_CP064389:305185-305292 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 8526.39 Da
• Isoelectric Point: 4.2092

>AT150105 WP_169941103.1 NZ_CP048833:5527515-5527745 [Pseudomonas multiresinivorans]
MEQGSVFQSNRSQAIRLPKAVALPEEVKRVDVVAVGRTRIISPAGESWDSWFDGDDVTADFMSEREQPADQEREGF

Nucleotide

• Length: 231 bp

>AT150105 NZ_CP064389:c305369-305309 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA