Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1523878..1524542 Replicon chromosome
Accession NZ_CP048833
Organism Pseudomonas multiresinivorans strain populi

Toxin (Protein)


Gene name VapC1 Uniprot ID -
Locus tag G4G71_RS06915 Protein ID WP_169936408.1
Coordinates 1523878..1524285 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag G4G71_RS06920 Protein ID WP_169936410.1
Coordinates 1524282..1524542 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G4G71_RS06890 1519415..1519954 + 540 WP_169936399.1 (2Fe-2S)-binding protein -
G4G71_RS06895 1519957..1521168 + 1212 WP_169936401.1 cytochrome c -
G4G71_RS06900 1521172..1522143 + 972 WP_169936403.1 XdhC family protein -
G4G71_RS06905 1522140..1522706 + 567 WP_169936405.1 nucleotidyltransferase family protein -
G4G71_RS06910 1522920..1523810 - 891 WP_169936407.1 alpha/beta fold hydrolase -
G4G71_RS06915 1523878..1524285 - 408 WP_169936408.1 type II toxin-antitoxin system VapC family toxin Toxin
G4G71_RS06920 1524282..1524542 - 261 WP_169936410.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
G4G71_RS06925 1524619..1525743 - 1125 WP_169936413.1 class I SAM-dependent methyltransferase -
G4G71_RS06930 1526087..1527079 + 993 WP_169936415.1 TRAP transporter substrate-binding protein -
G4G71_RS06935 1527187..1527963 + 777 WP_169936417.1 ferredoxin--NADP reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-126)

Antitoxin

SpoVT-AbrB domain

(11-48)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15258.39 Da        Isoelectric Point: 6.9682

>T150101 WP_169936408.1 NZ_CP048833:c1524285-1523878 [Pseudomonas multiresinivorans]
VNYLLDTNILIYLLKNRPESVAQRVNALPSDASLNMSFFTYAELLKGAERSSRKAEVRRQLDRLTRQIPVIHDSTPALCE
HYAAQFTRLKHAGTPIGANDLWIACHALALDATLVTHNTREFERIEGLVLEDWAS

Download         Length: 408 bp

>T150101 NZ_CP064388:c20107-19802 [Escherichia coli O104:H4]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTCCAGAGTGACATTATTGACAC
GCCCGGGCGACGGATGGTAATCCCCCTGGCCAGTGCCCGCCTGCTGTCAGATAAAGTCTCCCGTGAACTTTACCCGGTGG
TGCATGTCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAAGAAGTG
GCTGATCTCAGCCACTGGGAAAATGACATCAAAAATGCCATTAACCTGATGTTCTGGGGAATATAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9766.87 Da        Isoelectric Point: 4.0944

>AT150101 WP_169936410.1 NZ_CP048833:c1524542-1524282 [Pseudomonas multiresinivorans]
MPTSTLTTRVFMNGNSQAVRIPQEFRLEVSSVEITRAENGDLVIHPIPQDRGAALMEALRGFDEDFIEALEQDQRDQPPV
QDREEL

Download         Length: 261 bp

>AT150101 NZ_CP064388:c20327-20109 [Escherichia coli O104:H4]
ATGAAGCAGCGTATTACAGTGACAGTTGACAGCGACAGCTATCAGCTGCTCAAGGCGTATGACGTGAATATCTCCGGTCT
GGTCAGTACGACCATGCAGAACGAAGCCCGGCGACTGCGTGCTGAACGCTGGCAGGCTGAAAATCAGGAAGGGATGGCAG
AGGTCGCCAAGTTTATTGAAATGAACGGCTCTTTTGCCGATGAGAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References