Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 510559..511064 Replicon chromosome
Accession NZ_CP048833
Organism Pseudomonas multiresinivorans strain populi

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag G4G71_RS02390 Protein ID WP_169935258.1
Coordinates 510783..511064 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag G4G71_RS02385 Protein ID WP_169935257.1
Coordinates 510559..510786 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G4G71_RS02360 505821..506222 - 402 WP_169935252.1 GFA family protein -
G4G71_RS02365 506238..506951 - 714 WP_169935253.1 phytanoyl-CoA dioxygenase family protein -
G4G71_RS02370 506948..507874 - 927 WP_169935254.1 LysR family transcriptional regulator -
G4G71_RS02375 507950..508906 - 957 WP_169935255.1 agmatinase -
G4G71_RS02380 508933..510318 - 1386 WP_169935256.1 sodium:solute symporter -
G4G71_RS02385 510559..510786 + 228 WP_169935257.1 CopG family ribbon-helix-helix protein Antitoxin
G4G71_RS02390 510783..511064 + 282 WP_169935258.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G4G71_RS02395 511309..511596 - 288 WP_169935259.1 DUF2218 domain-containing protein -
G4G71_RS02400 511694..512611 + 918 WP_169935260.1 LysR family transcriptional regulator -
G4G71_RS02405 512655..513110 + 456 WP_169935261.1 GNAT family N-acetyltransferase -
G4G71_RS02410 513112..514119 - 1008 WP_169942479.1 AraC family transcriptional regulator -
G4G71_RS02415 514214..515164 - 951 WP_169935262.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-87)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10309.73 Da        Isoelectric Point: 5.0336

>T150100 WP_169935258.1 NZ_CP048833:510783-511064 [Pseudomonas multiresinivorans]
MSLQWTYKAAADLDAIYDHYVVLIGPEKALRAIQDIVEQVSPLANLDLSSSGVPSEVPGVRELGVERWPYQAAFRVKGRS
VQILRIDRVDNSG

Download         Length: 282 bp

>T150100 NZ_CP064387:5054375-5054773 [Escherichia coli O104:H4]
ATGCTGAAATTCATGCTGGATACCAATATCTGTATTTTCACTATTAAGAATAAACCAGTACATGTCAGAGAGCGGTTTAA
CCTGAATTCTGGCCGGATGTGTATAAGTTCTGTAACATTGATGGAGCTTATCTATGGGGCAGAAAAAAGTCAGATGCCAG
AACGCAATTTGGCGGTGATTGAAGGTTTCGTATCTCGTTTGGAAGTGCTTGATTATGATAGTGCTGCTGCGACGCATACC
GGGCAAATCAGGGCCGAGCTTGCCCGGCAGGGAAGGCCTGTTGGACCTTTTGACCAGATGATAGCGGGACATGCTCGCAG
TCGCGGTTTGATTGTGGTTACCAACAATACCCGAGAGTTTGAGCGAGTGGCGGGAATCAGACTAGAAGATTGGAGCTAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8259.21 Da        Isoelectric Point: 5.9478

>AT150100 WP_169935257.1 NZ_CP048833:510559-510786 [Pseudomonas multiresinivorans]
VTTVVSFRADDSLVAALDQLARATHRDRPYHLRQALAQYLERQSWHVAAIDEGVADADAGHLLEHAAIEAKWGLA

Download         Length: 228 bp

>AT150100 NZ_CP064387:5054148-5054375 [Escherichia coli O104:H4]
ATGGAAACTACTGTATTTTTAAGTAATCGCAGTCAGGCCGTCAGATTACCGAAAGCGGTCGCTCTGCCAGAGGATGTTAA
GAAAGTAGAAATTATTGCGATTGGTCGTACAAGAATCATCACTCCCGCCGGTGAGTCCTGGGACAGTTGGTTTGATGGCG
AAAATGTGAGTGCGGATTTTATGGATATCCGTGATCAACCCGCAATGCAGGAAAGGGAATCATTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References