Detailed information of TA system TA150094

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 3364415..3365056
• Replicon: chromosome
• Accession: NZ_CP048827
• Organism: Acinetobacter baumannii strain ABF9692

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: A0A5N0FZY3
• Locus tag: G3R47_RS16145
• Protein ID: WP_000607074.1
• Coordinates: 3364415..3364804 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: G3R47_RS16150
• Protein ID: WP_011860336.1
• Coordinates: 3364811..3365056 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G3R47_RS16130	3359533..3361728	-	2196	WP_001158905.1	TRAP transporter large permease subunit	-
G3R47_RS16135	3361916..3362482	-	567	WP_000651536.1	rhombosortase	-
G3R47_RS16140	3362560..3363645	-	1086	WP_000049106.1	hypothetical protein	-
G3R47_RS16145	3364415..3364804	-	390	WP_000607074.1	membrane protein	Toxin
G3R47_RS16150	3364811..3365056	-	246	WP_011860336.1	succinate dehydrogenase assembly factor 2	Antitoxin
G3R47_RS16155	3365256..3366428	+	1173	WP_001190545.1	acyl-CoA dehydrogenase family protein	-
G3R47_RS16160	3366478..3367968	-	1491	WP_000415136.1	NAD(P)/FAD-dependent oxidoreductase	-
G3R47_RS16165	3368150..3368527	-	378	WP_001216380.1	50S ribosomal protein L17	-
G3R47_RS16170	3368546..3369553	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15621.89 Da
• Isoelectric Point: 10.3890

>T150094 WP_000607074.1 NZ_CP048827:c3364804-3364415 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKVIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T150094 NZ_CP064387:c3657912-3657535 [Escherichia coli O104:H4]
ATGAATACATTACCCGACACTCACGTACGGGAGGCATCGGGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCACTATGGCCTCACGCTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGGATTTCACTGTGTGACGCGGTGAACTTTCTCGTTGAAAAATACGCGCTGGTACGTACCGACCAGCCGGGATTC
AGCGCAGGAGCCCCATCGCAGTTAATCAACAGCATTGATATTCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGGAA
CAATTACAGAATGGTAAATAACATTACCCAGGGCAAGCATCCGGAGGCAAAACGATGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9842.27 Da
• Isoelectric Point: 4.9001

>AT150094 WP_011860336.1 NZ_CP048827:c3365056-3364811 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT150094 NZ_CP064387:c3658336-3657959 [Escherichia coli O104:H4]
GTGTCAGACACACTTTCCGGGACAACGCATCCCGATGACAATGACGACCATCCCTGGTGGGGACTACCCTGCACAGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGTGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCATACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCATCACACTGTATGCGAAGGGGCTGACCTGCGAAGCCGATACCCTTGGCAGTTG
TGGTTACGCTTATCTGGCTGTTTATCCGACACCGGCAGAGCCCGCAATCACCGTATAA

Structures

Toxin

• AlphaFold DB: A0A5N0FZY3