Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 4901052..4901504 Replicon chromosome
Accession NZ_CP048815
Organism Caulobacter rhizosphaerae strain KCTC 52515

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag G3M57_RS22315 Protein ID WP_056762514.1
Coordinates 4901232..4901504 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0Q7VDJ2
Locus tag G3M57_RS22310 Protein ID WP_056762515.1
Coordinates 4901052..4901228 (+) Length 59 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G3M57_RS22285 4896760..4898085 - 1326 WP_056762523.1 Tol-Pal system protein TolB -
G3M57_RS22290 4898100..4898921 - 822 WP_163233100.1 energy transducer TonB -
G3M57_RS22295 4899092..4899613 - 522 WP_163233102.1 protein TolR -
G3M57_RS22300 4899618..4900316 - 699 WP_056762518.1 protein TolQ -
G3M57_RS22305 4900556..4900990 - 435 WP_163233104.1 YbgC/FadM family acyl-CoA thioesterase -
G3M57_RS22310 4901052..4901228 + 177 WP_056762515.1 hypothetical protein Antitoxin
G3M57_RS22315 4901232..4901504 + 273 WP_056762514.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G3M57_RS22320 4901506..4902552 - 1047 WP_056762512.1 Holliday junction branch migration DNA helicase RuvB -
G3M57_RS22325 4902674..4903288 - 615 WP_056762511.1 Holliday junction branch migration protein RuvA -
G3M57_RS22330 4903285..4903806 - 522 WP_188916278.1 crossover junction endodeoxyribonuclease RuvC -
G3M57_RS22335 4903957..4904469 + 513 WP_163233108.1 hypothetical protein -
G3M57_RS22340 4904474..4905409 - 936 WP_163233110.1 nucleoside hydrolase -
G3M57_RS22345 4905481..4906110 - 630 WP_163233112.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10111.58 Da        Isoelectric Point: 11.4750

>T150053 WP_056762514.1 NZ_CP048815:4901232-4901504 [Caulobacter rhizosphaerae]
MRRVVWTAEAIANLDSIFTYVAGFNAPAAARLAQRLQTAANSLVEHPERGRAASRGLRELATIHPYLIRYRFSDEAVVIL
RIRHGAQRPD

Download         Length: 273 bp

>T150053 NZ_CP064383:c4129161-4129054 [Escherichia coli O157:H7]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 59 a.a.        Molecular weight: 6088.67 Da        Isoelectric Point: 4.0229

>AT150053 WP_056762515.1 NZ_CP048815:4901052-4901228 [Caulobacter rhizosphaerae]
MKIEPSLFDEIDDDAEAAADARAEADVAAGRVISHEAVSRWLASWANGAPTPPPKVGD

Download         Length: 177 bp

>AT150053 NZ_CP064383:4129209-4129275 [Escherichia coli O157:H7]
GGTCTAGGTTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0Q7VDJ2

References