Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parE_1-relB/RelE(toxin)
Location 2064711..2065189 Replicon chromosome
Accession NZ_CP048812
Organism Halomonas socia strain CKY01

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag G3568_RS09830 Protein ID WP_163502007.1
Coordinates 2064905..2065189 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag G3568_RS09825 Protein ID WP_163502006.1
Coordinates 2064711..2064905 (+) Length 65 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G3568_RS09800 2060086..2061120 + 1035 WP_163502004.1 L-idonate 5-dehydrogenase -
G3568_RS09805 2061146..2061640 + 495 WP_205600972.1 TRAP transporter small permease subunit -
G3568_RS09810 2061650..2062942 + 1293 WP_163502005.1 TRAP transporter large permease -
G3568_RS09815 2062963..2063970 + 1008 WP_205600973.1 TRAP transporter substrate-binding protein DctP -
G3568_RS09825 2064711..2064905 + 195 WP_163502006.1 stability determinant Antitoxin
G3568_RS09830 2064905..2065189 + 285 WP_163502007.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G3568_RS09835 2065386..2065931 + 546 WP_163502008.1 cytochrome b -
G3568_RS09840 2066037..2066537 + 501 WP_163502009.1 hypothetical protein -
G3568_RS09845 2066670..2067083 + 414 WP_163502010.1 nucleoside diphosphate kinase regulator -
G3568_RS09850 2067129..2067737 + 609 WP_163502011.1 LysE family translocator -
G3568_RS09855 2067741..2068238 - 498 WP_163502012.1 copper chaperone PCu(A)C -
G3568_RS09860 2068348..2069997 - 1650 WP_163502013.1 isovaleryl-CoA dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1989256..2065189 75933


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10402.13 Da        Isoelectric Point: 7.2759

>T150039 WP_163502007.1 NZ_CP048812:2064905-2065189 [Halomonas socia]
MLPVVWLDGAISDLADIVRFVAQENPAAARRLKACLEAAPMVLAEHPYLSPAGRVSGTRELVVHPNYLIVYRVAASRVEI
VVVVHTRREYPPTE

Download         Length: 285 bp

>T150039 NZ_CP064383:c583538-583152 [Escherichia coli O157:H7]
ATGGGTGTGTATAAGGCAAGGCGATTCAGCCAAAGCACGAAAAAACTTGGTATTCACGATAAAGTTCTCATGGCTGCCGC
TGAAGAAGTGATGCAAGGCATATGGGAGGCTGATTTAGGTAGCGGTGTCATCAAAAAACGGTTACCCCTCCAACAAGGAA
AGAGTGGTGGAGCCAGAACAATTATCTTTTTTAAATCAGCAAATCATGTGTTTTTTTATGATGGTTGGTCCAAGAGTGGT
CTAAGCAGTAAAGGAAGCAAAGAAATCGAAGATGATGAACTGGCAGCCTACAAAAAAATGGCAAATGCATTTCTGGCCTT
TAGCAATAAGCAAATAGAGGATTTGATCGAAACTGGCTTCTTGATTGAGGTGAAAAATGAGCGATAA

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7189.99 Da        Isoelectric Point: 4.1509

>AT150039 WP_163502006.1 NZ_CP048812:2064711-2064905 [Halomonas socia]
MTTPLSPIVSEFETEEQAASYERWLREKVAKSLANPGPGVPHDEVMAQMDAIIDEAERRCNENT

Download         Length: 195 bp

>AT150039 NZ_CP064383:c583162-582833 [Escherichia coli O157:H7]
ATGAGCGATAAATTACAAATGATGCTGGAAGATGCAAAGGAACTGAATGCACTGGGCCTGATGTCTGATAGTGAGGTTGA
TGCCATTGCCGTCATGGTCAAAGCCCGTGAAGTCAGCGCCCGTATAGCCAAAGTCAAATCAATGACGGGTGAAGAGATCA
AAGCCATCCGCACCCGATACGGCATGTCACAATCCGTGCTGGCACATACAATGGGAATGTCAAAAGAAAGTGTCTCGAAA
TGGGAACGTAATGAAATAAAACCGAGCGGCCCGGCACTACGTATTTTGAATACATTGGCAATAAAAGGGCCGGAAGTTTT
TGCAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References