Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 1697828..1698220 Replicon chromosome
Accession NZ_CP048812
Organism Halomonas socia strain CKY01

Toxin (Protein)


Gene name EcnB Uniprot ID -
Locus tag G3568_RS08060 Protein ID WP_163501722.1
Coordinates 1698089..1698220 (+) Length 44 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID -
Locus tag G3568_RS08055 Protein ID WP_163501721.1
Coordinates 1697828..1697959 (+) Length 44 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G3568_RS08025 1693744..1694337 + 594 WP_163501717.1 hypothetical protein -
G3568_RS08030 1694334..1694705 + 372 WP_163501718.1 hypothetical protein -
G3568_RS08035 1694750..1695427 + 678 WP_163504208.1 DUF1007 family protein -
G3568_RS08040 1695424..1696476 + 1053 WP_163504209.1 nickel/cobalt transporter -
G3568_RS08045 1696473..1696898 - 426 WP_163501719.1 HIT family protein -
G3568_RS08050 1696994..1697740 + 747 WP_163501720.1 sulfite exporter TauE/SafE family protein -
G3568_RS08055 1697828..1697959 + 132 WP_163501721.1 entericidin A/B family lipoprotein Antitoxin
G3568_RS08060 1698089..1698220 + 132 WP_163501722.1 entericidin A/B family lipoprotein Toxin
G3568_RS08065 1698316..1698648 + 333 WP_163501723.1 hypothetical protein -
G3568_RS08070 1698645..1699250 - 606 WP_163501724.1 LysE family translocator -
G3568_RS08075 1699346..1700733 + 1388 Protein_1574 PLP-dependent aminotransferase family protein -
G3568_RS08080 1700787..1701782 - 996 WP_163501725.1 ion transporter -
G3568_RS08085 1701817..1702344 - 528 WP_163501726.1 acyl-CoA thioesterase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 44 a.a.        Molecular weight: 4283.87 Da        Isoelectric Point: 4.1035

>T150037 WP_163501722.1 NZ_CP048812:1698089-1698220 [Halomonas socia]
MKKAIALSFALLMAAGALAGCNTMEGAGEDVERGGETVQDAAN

Download         Length: 132 bp

>T150037 NZ_CP064380:10868-11170 [Vibrio furnissii]
ATGAGCAGTTATAAGCTTTCACCTTTAGCCCAGTCTGATCTCACTGATATTCGTCGTTACACCATAGAACATTGGGGCAG
TACTCAATGGTCCGTCTATTTTAATGAATTACAGGAATCGATGTCATTGCTGGCAAGTAACGAACTGATCGGAATTCAGA
TCCCGGAAATGGGAGAGCGATACTACCGTTTTCCTCTGAAGCACCATGTGATTTATTACATCACTCAGGAAGACCATATC
GTTATCGTCGCTGTGCTGGGTAAGCATATGTCTCCTGCAAAACATTTTGCGTCTATTTCTTAA

Antitoxin


Download         Length: 44 a.a.        Molecular weight: 4522.27 Da        Isoelectric Point: 4.6717

>AT150037 WP_163501721.1 NZ_CP048812:1697828-1697959 [Halomonas socia]
MKRLLAVLLLSLFTLSLLSGCNTMRGAGEDIEAGGEAIQRSAD

Download         Length: 132 bp

>AT150037 NZ_CP064380:10608-10853 [Vibrio furnissii]
ATGCAATCATTAACAGCAAATACAGCAAAAACCAAATTTGGCGATTTACTGATGAAGGTTCAGCGTGAACCCGTGCAAAT
CAGTAAAAATGGCTCACCGGTTGCGGTGATGATGTCCTGTGAAGAATATGAGCAATTAGAAGCACTCAAGATGATGCTGG
TTAAATCTCGTTTTGAACAGGCAGAAATTGATATCAGGAATGGCGATCTGGTCGATGGTGATGAATTTATGAAATCTCTG
GCTTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References