Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1094333..1094849 Replicon chromosome
Accession NZ_CP048812
Organism Halomonas socia strain CKY01

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag G3568_RS05160 Protein ID WP_163501265.1
Coordinates 1094580..1094849 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag G3568_RS05155 Protein ID WP_163501264.1
Coordinates 1094333..1094593 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G3568_RS05130 1090370..1091587 - 1218 WP_163501259.1 ABC transporter substrate-binding protein -
G3568_RS05135 1091805..1092845 + 1041 WP_163501260.1 peptidase C45 acyl-coenzyme A--6- aminopenicillanic acid acyl-transferase -
G3568_RS05140 1092842..1093096 - 255 WP_163501261.1 hypothetical protein -
G3568_RS05145 1093198..1093776 - 579 WP_163501262.1 DUF4202 domain-containing protein -
G3568_RS05150 1093915..1094238 + 324 WP_163501263.1 antibiotic biosynthesis monooxygenase -
G3568_RS05155 1094333..1094593 + 261 WP_163501264.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
G3568_RS05160 1094580..1094849 + 270 WP_163501265.1 Txe/YoeB family addiction module toxin Toxin
G3568_RS05165 1099515..1099808 - 294 WP_163501266.1 type I-E CRISPR-associated endoribonuclease Cas2 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1083542..1105763 22221


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(10-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-74)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10429.88 Da        Isoelectric Point: 9.4632

>T150036 WP_163501265.1 NZ_CP048812:1094580-1094849 [Halomonas socia]
MQTTSRLLCWTTASWNDYLYWQSQDKKTLKRINKLIADVQRSPFDGIGKPEPLKENLAGFWSRRIDETNRLVYAVDGGSI
TIISCRYHY

Download         Length: 270 bp

>T150036 NZ_CP064378:2707554-2707775 [Legionella pneumophila subsp. pneumophila]
ATGATTTTTATTGAAACTCCAATTTTTACAGAAGACGTGAAGGAATTATTATCTGATGAGGAGTATGCTGAGTTTCAAGA
GTATCTTGCTGATAATCCTTTAGCTGGAGACGTAATTCAGCAAACTGGCAAACTGGCAAACTGGCAAACTGCGAAAAGTT
CGATGGTCATTTCAAGGCAAATGGGAAGCGAGGCGGTGTTAGAATTATTTATTATTATGTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9490.60 Da        Isoelectric Point: 4.4536

>AT150036 WP_163501264.1 NZ_CP048812:1094333-1094593 [Halomonas socia]
VKIISFTEARNGLKAVLDGVVNDADTTVIARRDAEDAVVMSLEYYNSLMETVHLLRSPANAQHLNESIAQYRAGKATERE
LIDADD

Download         Length: 261 bp

>AT150036 NZ_CP064378:2707885-2708175 [Legionella pneumophila subsp. pneumophila]
ATGGATAAAAAATTATTTGAACGATTATACGAAAGTATGACTCAGATGAACGAAATTATTGATGGTGAGCGTGTTCCTTC
ACGTGAGTTCGTAGTGGATGCTGTTCATGTAAAAGAAATTAGAAAAAAAACAGGCCTAACCCAAGAAAAATTTTGTCATT
TAATTGATGTAAGTATTGGAACATTAAGAAATTGGGAGCAGGGGAGAAGAGAGCCAACAGGTCCTGCAAAAGCTCTTCTT
CGCGCAATAAATAAAGATCCTGAACATGTATTAGCAGCATTAGCTGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References