Detailed information of TA system TA150032

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PanAT/DUF4065(antitoxin)
• Location: 3781119..3782044
• Replicon: chromosome
• Accession: NZ_CP048810
• Organism: Pseudomonas bijieensis strain L22-9

Toxin (Protein)

• Gene name: panT
• Uniprot ID: -
• Locus tag: GN234_RS16515
• Protein ID: WP_176688782.1
• Coordinates: 3781718..3782044 (+)
• Length: 109 a.a.

Antitoxin (Protein)

• Gene name: panA
• Uniprot ID: -
• Locus tag: GN234_RS16510
• Protein ID: WP_176689598.1
• Coordinates: 3781119..3781646 (+)
• Length: 176 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GN234_RS16490	3777145..3777417	+	273	WP_109751975.1	oxidative damage protection protein	-
GN234_RS16500	3778503..3779498	+	996	WP_176688780.1	hypothetical protein	-
GN234_RS16505	3779903..3780376	+	474	WP_176688781.1	Rha family transcriptional regulator	-
GN234_RS16510	3781119..3781646	+	528	WP_176689598.1	SocA family protein	Antitoxin
GN234_RS16515	3781718..3782044	+	327	WP_176688782.1	hypothetical protein	Toxin
GN234_RS16520	3782298..3782627	+	330	WP_176688783.1	DHCW motif cupin fold protein	-
GN234_RS16525	3782689..3783096	+	408	WP_176688784.1	hypothetical protein	-
GN234_RS16530	3783297..3784346	+	1050	WP_176688785.1	DUF1016 family protein	-
GN234_RS16535	3784447..3785052	+	606	WP_109751971.1	biliverdin-producing heme oxygenase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Antitoxin SocA-like, Panacea domain (18-128)

Sequences

Toxin

Protein

• Length: 109 a.a.
• Molecular weight: 12428.03 Da
• Isoelectric Point: 7.1146

>T150032 WP_176688782.1 NZ_CP048810:3781718-3782044 [Pseudomonas bijieensis]
MNDPVYSHEHGYDGVLAVNISSIKPGVYYDPSCILTTNCHPFVRWESWVVYKEAAVFDASRLDLKVDAGEIVSHHPVSDD
LYNRVRAGFEISRHLPRKIGRFIRQNHF

Nucleotide

• Length: 327 bp

>T150032 NZ_CP064377:1678149-1678418 [Achromobacter xylosoxidans]
ATGAAGTGGACCAGCAAGGCGCTTTCCGATCTGGCGCGCTTGCATGAATTCCTGGCGGCGGTGAATAGGCCCGCGGCCGT
ACGGGCTGTGCAAGCGCTGGTCAAGGCTTCAAGTGTTTTGCCGACCAACTCCCGCATTGGCGAGCAGCTATTTCAGTTCG
AACCGCGCGAGGTACGCAGGATATTGGTCGGGGAGTACGAAATACGTTACGAGATCCGGGATTCGATCATCTACGTATTG
CGACTGTGGCACACCCGGGAGAACCGCTGA

Antitoxin

Protein

• Length: 176 a.a.
• Molecular weight: 20126.95 Da
• Isoelectric Point: 5.3239

>AT150032 WP_176689598.1 NZ_CP048810:3781119-3781646 [Pseudomonas bijieensis]
MAAYFLQKRGGRMAYIKLMKLLYLADRESMDRYSAPMSHDSHVSMAQGPVLSTTLNLITGQIESPAWRSWVTSEAKFEVS
LSRELNDLELLDELSDADLEIMDHVWEQFGRMKRWELVDYTHSHLPEWVDPGRSSTPINPRAVFKALGKDEQQAELLARE
LFERKSLGRAVSELI

Nucleotide

• Length: 528 bp

>AT150032 NZ_CP064377:1677877-1678143 [Achromobacter xylosoxidans]
ATGAGTCCCGCAACCAAGGTGCTGACCGCACATGTGCCGCTTCCGTTGGCCGAGAAGGTCGATCAGATGGCTGTGCGCCT
GGACCGATCTCGCGGCTGGATCGTGAAGCAGGCACTGTCCGCTTGGATTGCCCAAGAGGAGGAACGTGACAAGCTCACCG
AGCAAGCGCTTGCTGACGTGGATGCTGGTCGGATTGTGGATGACCAAGCCGTGCAAGCCTGGGCGGAGAGCCTGGGCTCT
GACCAGCCATTGCCGCTGCCGCGATGA