Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 3433523..3434119 Replicon chromosome
Accession NZ_CP048810
Organism Pseudomonas bijieensis strain L22-9

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag GN234_RS15015 Protein ID WP_109752224.1
Coordinates 3433523..3433825 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GN234_RS15020 Protein ID WP_109752223.1
Coordinates 3433829..3434119 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GN234_RS15000 3430316..3431515 + 1200 WP_176689595.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
GN234_RS15005 3431508..3432605 + 1098 WP_176688710.1 cobalt-precorrin-5B (C(1))-methyltransferase -
GN234_RS15010 3432602..3433330 + 729 WP_176688711.1 cobalt-precorrin-6A reductase -
GN234_RS15015 3433523..3433825 + 303 WP_109752224.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GN234_RS15020 3433829..3434119 + 291 WP_109752223.1 putative addiction module antidote protein Antitoxin
GN234_RS15025 3434278..3434676 + 399 WP_135843484.1 DUF2946 domain-containing protein -
GN234_RS15030 3434724..3435203 + 480 WP_176688712.1 copper chaperone PCu(A)C -
GN234_RS15035 3435261..3435659 + 399 WP_176688713.1 DUF2946 domain-containing protein -
GN234_RS15040 3435744..3437870 + 2127 WP_176688714.1 TonB-dependent copper receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(5-94)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11268.84 Da        Isoelectric Point: 9.5454

>T150031 WP_109752224.1 NZ_CP048810:3433523-3433825 [Pseudomonas bijieensis]
MIEFEHSRVFSSWLSGLKDISGKARIIARLRSAEHGNFGDCEPVGSAVYEMRIHSGPGYRVYFSRRGPVFYLLLVGGDKS
TQKRDITRAIQMAQTMGNEE

Download         Length: 303 bp

>T150031 NZ_CP064377:621374-621655 [Achromobacter xylosoxidans]
GTGCCCGCAGTTGAATGGTCGTCCGCCGCCCGGGCCGACCTGTTGGCCATAGTCGACTACATATCAGATGACAATCCAGA
CGCTGCCCAGCGTCTGAAAGACGATATTGAAACGAAGGCGGCGCAACTGCCCGCCCGTCCCGCGCTGTACCGCCCCGGAA
GGATCGCCGGTACCCGCGAAATGGTCGTTCGCGCGAATTACATCATCGTGTATGCGGCGGATGCGCTGGCCGTGCGGATC
CTGCGCATCTTGCATGCCGCGCAGCAATGGCCGCCGCAGTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10431.98 Da        Isoelectric Point: 4.8096

>AT150031 WP_109752223.1 NZ_CP048810:3433829-3434119 [Pseudomonas bijieensis]
MTEEFTRFDAATYLKTPEEMAAYLDACFEEDAGDGVLVRAALNDIARAKGMTQIARDAGLGRESLYKALGSAGNPEFTTI
MKVMKVLGLRLHATTI

Download         Length: 291 bp

>AT150031 NZ_CP064377:621091-621387 [Achromobacter xylosoxidans]
ATGCCCCAGACCTCGATGCTCCACGTCCGCGTGGACGACAAGCTCAAAGCCGACGCCACCGAAAAGCTGGCCGAATTCGG
CCTGACGATTTCCGACGCCGTGCGCATCCTGCTCACGCGGGTGGCCAAGGAGGGCGGCCTGCCCGCCGGGTTGACCACCG
ATGCCCAGGCGCACGACGCGTGGTTCCGCGCCAAAGTCCAGGAAGCCCTGGCCGATACGGGGCCGGCGGTGCCGCACCAG
CAGGTCATGGATGAAGCCCAGGCGCTGATCGACAGGAAGCGCCGTGCCCGCAGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References