Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1976058..1976203 Replicon chromosome
Accession NZ_CP048800
Organism Klebsiella pneumoniae strain EGKP4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1976094..1976196 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1976058..1976203 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G4I41_RS09630 1971188..1973248 + 2061 WP_004151449.1 oligopeptidase B -
G4I41_RS09635 1973252..1973911 - 660 WP_002911407.1 exodeoxyribonuclease X -
G4I41_RS09640 1973990..1974220 - 231 WP_002911406.1 DNA polymerase III subunit theta -
G4I41_RS09645 1974333..1974707 + 375 WP_004151448.1 CopC domain-containing protein YobA -
G4I41_RS09650 1974711..1975580 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
G4I41_RS09655 1975597..1975935 + 339 WP_002911404.1 YebY family protein -
- 1976058..1976203 - 146 - - Antitoxin
- 1976094..1976196 + 103 - - Toxin
G4I41_RS09660 1976571..1976714 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
G4I41_RS09665 1976819..1977787 - 969 WP_004151446.1 VirK/YbjX family protein -
G4I41_RS09670 1977944..1978597 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
G4I41_RS09675 1978594..1978785 - 192 WP_002911395.1 YebW family protein -
G4I41_RS09680 1978883..1979122 - 240 WP_002911393.1 YebV family protein -
G4I41_RS09685 1979238..1980671 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T150011 NZ_CP048800:1976094-1976196 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT150011 NZ_CP048800:c1976203-1976058 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References