Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | pmenTA/darT(toxin) |
Location | 4274424..4276153 | Replicon | chromosome |
Accession | NZ_CP048796 | ||
Organism | Providencia vermicola strain P8538 |
Toxin (Protein)
Gene name | pmenT | Uniprot ID | - |
Locus tag | G3341_RS19470 | Protein ID | WP_154623506.1 |
Coordinates | 4274424..4275068 (+) | Length | 215 a.a. |
Antitoxin (Protein)
Gene name | pmenA | Uniprot ID | - |
Locus tag | G3341_RS19475 | Protein ID | WP_154623505.1 |
Coordinates | 4275080..4276153 (+) | Length | 358 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
G3341_RS19455 | 4272010..4272840 | + | 831 | WP_163863435.1 | formate dehydrogenase accessory sulfurtransferase FdhD | - |
G3341_RS19460 | 4272844..4273623 | - | 780 | WP_154624784.1 | transferase | - |
G3341_RS19465 | 4273855..4274424 | + | 570 | WP_163863437.1 | DUF4433 domain-containing protein | - |
G3341_RS19470 | 4274424..4275068 | + | 645 | WP_154623506.1 | DUF4433 domain-containing protein | Toxin |
G3341_RS19475 | 4275080..4276153 | + | 1074 | WP_154623505.1 | macro domain-containing protein | Antitoxin |
G3341_RS19480 | 4276255..4277619 | - | 1365 | WP_163863439.1 | tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE | - |
G3341_RS19485 | 4277719..4279368 | - | 1650 | WP_154623503.1 | membrane protein insertase YidC | - |
G3341_RS19490 | 4279371..4279631 | - | 261 | WP_014657163.1 | membrane protein insertion efficiency factor YidD | - |
G3341_RS19495 | 4279595..4279954 | - | 360 | WP_163863441.1 | ribonuclease P protein component | - |
G3341_RS19500 | 4279976..4280119 | - | 144 | WP_004906236.1 | 50S ribosomal protein L34 | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 215 a.a. Molecular weight: 25047.66 Da Isoelectric Point: 6.9106
>T150005 WP_154623506.1 NZ_CP048796:4274424-4275068 [Providencia vermicola]
MAYMNLNPEKALIWRITHRQNIPWLFANGLYAGNSEHYSPNWVTIGNTDLINRRNQRHVPIQPNGVLNDYVPFYFTPFSP
MMYNIYTGRGGVRKVPNDDIIILVSSMYKIAALKIPFVFTDRHAYPVTSQFYNQLTDLAEIDWALLQQRNFHRDPDDPEK
VERYQAEALIYKHVPMEALLGAVCYTKETQLELQAKASQLEIHLDIHCIPNWYF
MAYMNLNPEKALIWRITHRQNIPWLFANGLYAGNSEHYSPNWVTIGNTDLINRRNQRHVPIQPNGVLNDYVPFYFTPFSP
MMYNIYTGRGGVRKVPNDDIIILVSSMYKIAALKIPFVFTDRHAYPVTSQFYNQLTDLAEIDWALLQQRNFHRDPDDPEK
VERYQAEALIYKHVPMEALLGAVCYTKETQLELQAKASQLEIHLDIHCIPNWYF
Download Length: 645 bp
>T150005 NZ_CP064374:c621119-620976 [Enterococcus faecalis]
ATGAGCGTACTTCCAAAATTTACAGAAAGGAGAGGCCTGTTGTCAGCATATGAGACAATTCAGACGATCCTAGGTTTTGG
TATGTTTACCATTGCTTTGATTGCACTGATTGTGAAATTGCTTAAAAATGACAAGAAAAAATAA
ATGAGCGTACTTCCAAAATTTACAGAAAGGAGAGGCCTGTTGTCAGCATATGAGACAATTCAGACGATCCTAGGTTTTGG
TATGTTTACCATTGCTTTGATTGCACTGATTGTGAAATTGCTTAAAAATGACAAGAAAAAATAA
Antitoxin
Download Length: 358 a.a. Molecular weight: 40807.28 Da Isoelectric Point: 7.8198
>AT150005 WP_154623505.1 NZ_CP048796:4275080-4276153 [Providencia vermicola]
MIEFTQGNLLEADVEALVNTVNTVGVMGKGIALMFKERFPANMAAYAKACKTHEVQTGKMFVTETGELMGPRWIVNFPTK
QHWRAKSQIQWIIDGLLDLRNFIEENHVKSIAIPPLGAGNGGLNWDDVKPHIVEILGDIQNVKIIVYEPIAKYQNVAKPK
GVEKLTPARALIAELIRRYWVMGMDCSLLEIQKLAWFLERTIEAEGLRNPLNLRFEARNYGPYADKLRHLLNGLDGSYLK
SEKRISDCSPLDVIWFNDDKRATIELYLKTEAKDYLSALEKTTKLIDGFESPFGIELLSTVDWLLYKKQSSPNIESLLEG
MRQWPAGDRWAQRKLRLFDSNKLELALNHLKQIPFYS
MIEFTQGNLLEADVEALVNTVNTVGVMGKGIALMFKERFPANMAAYAKACKTHEVQTGKMFVTETGELMGPRWIVNFPTK
QHWRAKSQIQWIIDGLLDLRNFIEENHVKSIAIPPLGAGNGGLNWDDVKPHIVEILGDIQNVKIIVYEPIAKYQNVAKPK
GVEKLTPARALIAELIRRYWVMGMDCSLLEIQKLAWFLERTIEAEGLRNPLNLRFEARNYGPYADKLRHLLNGLDGSYLK
SEKRISDCSPLDVIWFNDDKRATIELYLKTEAKDYLSALEKTTKLIDGFESPFGIELLSTVDWLLYKKQSSPNIESLLEG
MRQWPAGDRWAQRKLRLFDSNKLELALNHLKQIPFYS
Download Length: 1074 bp
>AT150005 NZ_CP064374:620857-621043 [Enterococcus faecalis]
TGTGCTAGAATGTAGATGAAAAGAGAGATATGCGTCAACATACCTCTCTAGTGTAGAGCCGTTTGAGACGGTGACCGATT
GTATTATTTAAAAATAACCGTACTGGTCAAAGTAGATGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGTG
CAATCAAAGCAATGGTAAACATACCAA
TGTGCTAGAATGTAGATGAAAAGAGAGATATGCGTCAACATACCTCTCTAGTGTAGAGCCGTTTGAGACGGTGACCGATT
GTATTATTTAAAAATAACCGTACTGGTCAAAGTAGATGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGTG
CAATCAAAGCAATGGTAAACATACCAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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