Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1946620..1946765 Replicon chromosome
Accession NZ_CP048778
Organism Klebsiella pneumoniae strain EGKP7

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1946656..1946758 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1946620..1946765 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G4D19_RS09420 1941750..1943810 + 2061 WP_004151449.1 oligopeptidase B -
G4D19_RS09425 1943814..1944473 - 660 WP_002911407.1 exodeoxyribonuclease X -
G4D19_RS09430 1944552..1944782 - 231 WP_002911406.1 DNA polymerase III subunit theta -
G4D19_RS09435 1944895..1945269 + 375 WP_004151448.1 CopC domain-containing protein YobA -
G4D19_RS09440 1945273..1946142 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
G4D19_RS09445 1946159..1946497 + 339 WP_002911404.1 YebY family protein -
- 1946620..1946765 - 146 - - Antitoxin
- 1946656..1946758 + 103 - - Toxin
G4D19_RS09450 1947133..1947276 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
G4D19_RS09455 1947381..1948349 - 969 WP_004151446.1 VirK/YbjX family protein -
G4D19_RS09460 1948506..1949159 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
G4D19_RS09465 1949156..1949347 - 192 WP_002911395.1 YebW family protein -
G4D19_RS09470 1949445..1949684 - 240 WP_002911393.1 YebV family protein -
G4D19_RS09475 1949800..1951233 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T149958 NZ_CP048778:1946656-1946758 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT149958 NZ_CP048778:c1946765-1946620 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References