149933

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 551672..552375 Replicon chromosome
Accession NZ_CP048736
Organism Enterobacter sp. T2

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag G0034_RS02630 Protein ID WP_179120480.1
Coordinates 552034..552375 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag G0034_RS02625 Protein ID WP_179120479.1
Coordinates 551672..552013 (+) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G0034_RS02590 (546822) 546822..547697 + 876 WP_179120476.1 GTPase family protein -
G0034_RS02595 (547941) 547941..548657 + 717 WP_160862976.1 WYL domain-containing protein -
G0034_RS02600 (548693) 548693..549145 + 453 WP_031593203.1 hypothetical protein -
G0034_RS02605 (549217) 549217..549690 + 474 WP_031593204.1 hypothetical protein -
G0034_RS02610 (549811) 549811..550632 + 822 WP_179120477.1 DUF932 domain-containing protein -
G0034_RS02615 (550663) 550663..551106 + 444 WP_160862973.1 antirestriction protein -
G0034_RS02620 (551119) 551119..551661 + 543 WP_179120478.1 DNA repair protein RadC -
G0034_RS02625 (551672) 551672..552013 + 342 WP_179120479.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
G0034_RS02630 (552034) 552034..552375 + 342 WP_179120480.1 TA system toxin CbtA family protein Toxin
G0034_RS02635 (552634) 552634..553641 + 1008 WP_000528271.1 restriction endonuclease -
G0034_RS02640 (553917) 553917..555758 - 1842 WP_179120481.1 response regulator receiver domain -
G0034_RS23240 (555748) 555748..556407 - 660 WP_286079247.1 HAMP domain-containing sensor histidine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-109)

Antitoxin

Antitoxin CbeA

(13-111)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12702.69 Da        Isoelectric Point: 9.6548

>T149933 WP_179120480.1 NZ_CP048736:552034-552375 [Enterobacter sp. T2]
MKTLPATNPQAAKLCLSPVAVWQMLLARLLEQHYGLTLNDTPFSDETVIQEHIDAGISLADAVNFLVEKYGLVRIDRRGF
GWQEQSPYLRAVDILRARQATGLLKRNRISAAR

Download         Length: 342 bp

>T149933 NZ_CP064351:c432368-432051 [Vibrio cholerae C6706]
ATGCAAAATAAACAATATAAGCTCAGCCAATTAGCCCAAGAGCACTTACTCAAGATTAAACACTACACCATTGAAAATTT
CGCTGAAGCGCAGTGGCAAAAATATAAGTCGACCTTGCTTTCAGGTTTCCAAACTCTTGCGGATAACCCAGGACTAGGAA
AAAGCTGTGAAGATATTTACCAAAATGGTTTTTACTTTCCAGTGGGGAAACACATGGCTTATTACACCAAAGAAGCAAAC
TTCATTCTCATTGTTGCGGTATTAGGGCAATCACAACTGCCCCAAAAGCATCTCAAACAGTCACGCTTTGTTTCTTAG

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12740.40 Da        Isoelectric Point: 6.7345

>AT149933 WP_179120479.1 NZ_CP048736:551672-552013 [Enterobacter sp. T2]
MKSTDSENDSFLKWGLNRNVTPCFGARLVQEGNRLHYLADRVSITGKFSEAECLKLDVAFPHFISQMESMLTTGEMNPRH
AHCVTLYHNGFTCEADTLGSCGYVYIAVYSTHR

Download         Length: 342 bp

>AT149933 NZ_CP064351:c432629-432387 [Vibrio cholerae C6706]
ATGCACACACTAACAGCAAATGATGCTAAACGAAATTTTGGTGAACTTCTTCTAAGCGCACAACGCGAACCTGTCATCAT
CAGCAAAAACAGTAAGAATACTGTCGTTGTCATGTCCATTAAGGACTTTGAAGAACTTGAAGCAATGAAACTCGATTATC
TCAAACACTGCTTTGAGTCTGCTCAGAAAGACTTAGATAGTGGCAAAACCGTTGATGGTGCCACTTTTCTAAACACCCTT
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References