Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1260768..1261518 Replicon chromosome
Accession NZ_CP048732
Organism Mammaliicoccus sciuri strain NWAF26

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag G3T51_RS06265 Protein ID WP_101494413.1
Coordinates 1261411..1261518 (+) Length 36 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag G3T51_RS06260 Protein ID WP_152291561.1
Coordinates 1260768..1261367 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G3T51_RS06235 1256131..1256892 + 762 WP_152291560.1 acetylglutamate kinase -
G3T51_RS06240 1257702..1258829 + 1128 WP_048539836.1 tRNA epoxyqueuosine(34) reductase QueG -
G3T51_RS06245 1258833..1259306 + 474 WP_025904798.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
G3T51_RS06250 1259341..1259481 - 141 WP_162841915.1 hypothetical protein -
G3T51_RS06255 1259568..1260719 + 1152 WP_107611084.1 N-acetylglucosamine-6-phosphate deacetylase -
G3T51_RS06260 1260768..1261367 + 600 WP_152291561.1 glucosamine-6-phosphate isomerase Antitoxin
G3T51_RS06265 1261411..1261518 + 108 WP_101494413.1 hypothetical protein Toxin
G3T51_RS06270 1261671..1263059 + 1389 WP_048539839.1 class II fumarate hydratase -
G3T51_RS06275 1263149..1264675 + 1527 WP_075578060.1 exopolyphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(134-195)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4130.43 Da        Isoelectric Point: 3.7615

>T149928 WP_101494413.1 NZ_CP048732:1261411-1261518 [Mammaliicoccus sciuri]
MVQDLEDVKELGKEMEQISEQNDEAFEEKKSEQES

Download         Length: 108 bp

>T149928 NZ_CP064351:c393545-393048 [Vibrio cholerae C6706]
ATGATGAATACGGTACTTCTCGATAAAGATAAGCACGATAGGAACCGTTTCAATTGTGGCACTGAAGCACTCAACAATTA
CTTAAAAGTAATGGCGAGTCAGCAAGCCAAAAAAGACAACACCAGAACCTTCGTTTTGGAAGATGACAATAACAGTGCTT
ATATCATCGGCTTTTACACTCTGACTATGACGCCCATTGATTTGAAAGCCTTGCCCGACAAGTTACAAAAGAAGCACCAA
TCCTCAACCTCTGGAGGGCTCATTGCTCGTTTAGCTGTCGACGATAGATACAAAGGAAAAGGTTTTGGTGAGTGGCTACT
CATTGACGCTCTCAGAAAGCTACTCGCAGCCAGTGACAGTGTAGCGTTCCCTGTTGTCATTGTTGATGCCAAAGATGGTG
CAAAACATTTCTATGAGCGCTATGGGTTTCAAGCGTTTCAAGATGCCGAAAACAAACTCTTCATCACCATTGCTGATATC
AGAGCAAGCTTAGGCTAG

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22262.12 Da        Isoelectric Point: 4.9758

>AT149928 WP_152291561.1 NZ_CP048732:1260768-1261367 [Mammaliicoccus sciuri]
MALNFKVFETKDIAARYAADVVRKQFNSDSTSVVGVHLEAEQTSFFDELLDDVKKNPVNFSQIHILDFDGKEDYYTELGV
PAKQVLKTDVGSDVEAFIKEKVNTDKKKNKLMLDVVTLTEDSRTGLDYNQAIHPAREVIVLVTGKEKAKAVSQLYQEPAN
GSAESAKLKQHRMVTVVLDNEAAQGLPEDVRSYFSIQFS

Download         Length: 600 bp

>AT149928 NZ_CP064351:c393814-393542 [Vibrio cholerae C6706]
ATGGCAACGACTTTGCCTCGCATCACCGCTAGAGTTGATGTCGATACTCAAGATTTACTCGCTAAGGCTGCTGCTCTTGC
TGGTATGTCTAGTATTAACTCATTTGTTTTGAATGCAGCAATCGAAAAAGCAAAACAAGTCATTGAACGTGAGCAAGCTC
TAAAGCTTAGCCAAGCTGATGCCGTATTGCTGATGGAAGCTCTTGATAATCCAGCTGTAGTAAATGCAAAGCTCAAATTG
GCATCCGAACGTTATGAGAGCAAAACTCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References