149921

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4680639..4681000 Replicon chromosome
Accession NZ_CP048712
Organism Xanthomonas citri strain UnB-XtecTG02-2

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag G3566_RS19940 Protein ID WP_005914328.1
Coordinates 4680639..4680773 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag G3566_RS19945 Protein ID WP_003486606.1
Coordinates 4680848..4681000 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G3566_RS19925 4677669..4678712 - 1044 WP_194272002.1 MBL fold metallo-hydrolase -
G3566_RS19930 4678742..4680031 - 1290 WP_194272003.1 tryptophan--tRNA ligase -
G3566_RS19935 4680204..4680413 - 210 WP_016904514.1 CsbD family protein -
G3566_RS19940 4680639..4680773 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
G3566_RS19945 4680848..4681000 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
G3566_RS19950 4681107..4682030 - 924 WP_007966941.1 arginase -
G3566_RS19955 4682351..4682803 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
G3566_RS19960 4682867..4683226 + 360 WP_003486613.1 hypothetical protein -
G3566_RS19965 4683323..4684240 + 918 WP_089096274.1 hypothetical protein -
G3566_RS19970 4684237..4684779 + 543 WP_003486615.1 GTPase -
G3566_RS19975 4685259..4685942 + 684 WP_007966938.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T149921 WP_005914328.1 NZ_CP048712:c4680773-4680639 [Xanthomonas citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T149921 NZ_CP064334:c2526201-2525893 [Xylella fastidiosa subsp. fastidiosa]
GTGACCATCACAAAGAAAATCAATGTCTCCGAACTGCCAGAGTTCGATGCCGCCGAATACCTGAACAGCGAAGAGGAGGT
AGCCGCGTATCTCACGGCTGTTCTTGAAGAAAACGATCCAGCACTGTTAGCGGCTGCGCTTGGTGACATTGCCCGTTCAC
GTGGTATGTCTCAGATTGCGAAGGATTCTGGCATCACGCGGGAAGCTCTATACAAGGCCCTTCGGCCTGGTAGTGAACCA
CGCTTCGATACGATAAGCCGCGTCTGTACCGCCCTAGGTATACGTCTAGTAGCGCAACCAATGCATTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT149921 WP_003486606.1 NZ_CP048712:c4681000-4680848 [Xanthomonas citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT149921 NZ_CP064334:c2526504-2526205 [Xylella fastidiosa subsp. fastidiosa]
ATGACCTACACGCTAAAACGACTTGAAGGGTTCTCTGACTGGCTAAAGGGCCTAAAGGATGGGCTGGCAAGGCAGCGCCT
CATCAAGCGCTTACGCAAGGTGCAGCTCGGCAACTTTGGAGACGTGCAGCCGGTGGGTGAAGGCGTGTTTGAAATGCGCG
AACACTTCGGACCTGGCTGGCGTATGTACTACGTGCAGCGAGGCAGCTTTCTCATCGTGATGCTCGGCGGCGGCGACAAG
TCAACGCAGCAATCAGACATTCGTCGGGCCATTGAGCTAGCAAAATCTTTAGAGGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References