Detailed information of TA system TA149920

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 64522..65066
• Replicon: chromosome
• Accession: NZ_CP048712
• Organism: Xanthomonas citri strain UnB-XtecTG02-2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: G3566_RS00280
• Protein ID: WP_194272170.1
• Coordinates: 64767..65066 (+)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A7Z7EKF2
• Locus tag: G3566_RS00275
• Protein ID: WP_029818122.1
• Coordinates: 64522..64779 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G3566_RS00260	59636..61123	-	1488	WP_194272168.1	ribonuclease H-like domain-containing protein	-
G3566_RS00265	61120..63615	-	2496	WP_167382218.1	DEAD/DEAH box helicase	-
G3566_RS00270	63793..64455	+	663	WP_194272169.1	hemolysin III family protein	-
G3566_RS00275	64522..64779	+	258	WP_029818122.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
G3566_RS00280	64767..65066	+	300	WP_194272170.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
G3566_RS00290	65246..66145	-	900	WP_099803356.1	SDR family NAD(P)-dependent oxidoreductase	-
G3566_RS00295	66204..66941	-	738	WP_007964860.1	SDR family oxidoreductase	-
G3566_RS00300	67067..67978	+	912	WP_194272171.1	LysR family transcriptional regulator	-
G3566_RS00305	68193..69266	-	1074	WP_194273029.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11216.01 Da
• Isoelectric Point: 10.1557

>T149920 WP_194272170.1 NZ_CP048712:64767-65066 [Xanthomonas citri]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHVMRSVRALRGNRLSR

Nucleotide

• Length: 300 bp

>T149920 NZ_CP064334:c1598308-1598054 [Xylella fastidiosa subsp. fastidiosa]
ATGAAGCGTAAGCACGCTAAAACTCTCAGCGCTATATACACACGCCCTGTTTCGGCCAACATTCAATGGCGCGATATTGA
AGCGCTGTTCGTGGAGCTTGGAGCGAAAGTAGAAGAACGTGAAGGTTCTCGTATGTTGGTGCGACTGTTCGGTGAACGTC
GGATATTCCACCGGCCCCACCCTTCTCCTAACACTGACAAGGGTGCTGTTGAATCAATCCGAGCTTGGTTGAAATCGAAC
GGAGTTACACCATGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9632.12 Da
• Isoelectric Point: 8.6223

>AT149920 WP_029818122.1 NZ_CP048712:64522-64779 [Xanthomonas citri]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVADGRTLSHEQAQQRM
ARWLK

Nucleotide

• Length: 258 bp

>AT149920 NZ_CP064334:c1598057-1597722 [Xylella fastidiosa subsp. fastidiosa]
ATGAAGAACATCATGACTATTGAGAGCTTTAAAGCCATCATTACCTATGATCCGGAGATCGACATGTTTCGCGGTGAATT
TGTGGGTATCAATGGTGGTGCTGATTTCTATGCAAAAGACCTTAAGGGTCTTCGTCGAGAAGGAGCTATTTCTCTGAAGG
TATTTTTGGAAGCCTGCAAAGAAGATAGCGTGGAACCACGTAAATGCTACTCAGGGAAGTTCAATGCAAGGATTTCTCCT
GAACTGCATGCTTTGGCTTCTGAAGCCGCAGCAGCACAGGGCATCAGTTTGAACCAATTTGTAGAACAAGCGATTCAGCA
TGAAGTCCACACCTGA

Structures

Antitoxin

• AlphaFold DB: A0A7Z7EKF2