Detailed information of TA system TA149918

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 3395536..3396900
• Replicon: chromosome
• Accession: NZ_CP048711
• Organism: Kineobactrum salinum strain M2

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: G3T16_RS14975
• Protein ID: WP_163495939.1
• Coordinates: 3395536..3396234 (-)
• Length: 233 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: G3T16_RS14980
• Protein ID: WP_163497127.1
• Coordinates: 3396301..3396900 (-)
• Length: 200 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G3T16_RS14965	3391434..3391646	-	213	WP_163495937.1	hypothetical protein	-
G3T16_RS14970	3391730..3393922	-	2193	WP_163495938.1	hypothetical protein	-
G3T16_RS14975	3395536..3396234	-	699	WP_163495939.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
G3T16_RS14980	3396301..3396900	-	600	WP_163497127.1	AbiEi antitoxin N-terminal domain-containing protein	Antitoxin
G3T16_RS14985	3397079..3397333	+	255	WP_163495940.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-
G3T16_RS21210	3397327..3397527	+	201	WP_197911693.1	type II toxin-antitoxin system PemK/MazF family toxin	-
G3T16_RS14995	3398169..3398687	+	519	WP_163495941.1	hypothetical protein	-
G3T16_RS15000	3398918..3399295	-	378	WP_163495942.1	site-specific integrase	-
G3T16_RS15005	3400193..3400834	-	642	WP_163495943.1	LysE family translocator	-
G3T16_RS15010	3400978..3401160	+	183	WP_163495944.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3383086..3431050	47964

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (36-228)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (6-53)

Sequences

Toxin

Protein

• Length: 233 a.a.
• Molecular weight: 26092.69 Da
• Isoelectric Point: 4.9712

>T149918 WP_163495939.1 NZ_CP048711:c3396234-3395536 [Kineobactrum salinum]
MNERNVAASVRARLLDRARGTGQDFNLVLTRYAIERLLYRISISSHADQFLLKGALLFDLWFDIPHRPTRDADFLGFGSA
ELPDIESVFREICTIESHDGVVFQPDTVHAAEIRKEANYAGVRVMLLGVIDSARCQIQIDIGFGDAVTPSPEDVEYPIML
TEFAAPKLRAYPRYTVVAEKVEALSSLGIANSRMKDYFDLWILLAQHTDFDGDILRQAVQSTFDRRNTALPG

Nucleotide

• Length: 699 bp

>T149918 NZ_CP064334:1405351-1405656 [Xylella fastidiosa subsp. fastidiosa]
ATGAATAATGAGACTTTTAGTCGATACGACACCGCTGACTATCTCAAAACCGAAGAAGATATTGCGGCTTATATGGAAGC
CGTCATGGAAGAAGGTGGTAGGGATAATCCTGCTTTTATTGCACGGGCACTTGGTGCTGTCGCTCGTGCTCGTAATTTAA
GTCAGCTTGCTCGTGACGTTGGCATGTCCAGGCAAGGACTAGACAAGGCACTCTCTAACGACGGCAACCCAAGCTTCTCA
ACCATCTTAAAAGTGGCTAAAGCGCTTGGTTTACGGATGTCATTCACACCTTCCTCTATGAGTTAA

Antitoxin

Protein

• Length: 200 a.a.
• Molecular weight: 22413.17 Da
• Isoelectric Point: 10.1917

>AT149918 WP_163497127.1 NZ_CP048711:c3396900-3396301 [Kineobactrum salinum]
MEISYQAILDLASQHGLIRPRDLNERGLPTVALTRLVRQGRLQRVGRGLYAIPNRLVSENSALAEVARKHPQAIICLLSA
LRLRELTTQSPFEVWVAIPNKARAPKMDYPPLRVVRFSGAALTEGIEEDIIDGVPVRVTNVARTVADCFKFRNKIGLDVA
LEALQDAWRAKRVGMDELWRYATICRVANVMRPYMESLP

Nucleotide

• Length: 600 bp

>AT149918 NZ_CP064334:1405051-1405347 [Xylella fastidiosa subsp. fastidiosa]
ATGGTCGAACTCATCAAAACCAGCACTTTTGATGCTTGGATAAACAGCTTACGTGACCGCAAAGCAGCCGCCAGAATTCA
AGCGCGTCTTGATCGGCTCGCACTTGGCAATCCCGGCGACGTGAAGCCTGTGGGTGCTGGCATCTCAGAAATGAGGATCG
ACCATGGGCCCGGATATCGGATCTATTTTATGAAGCATGGTGCAGTACTGATTCTCTTACTTTGCGGTGGCGATAAATCG
TCACAAGTACGAGATATAGAGCAGGCTAAGGCACTGGCTGCACTGTGGAAGGATTAG