Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 2938592..2939139 Replicon chromosome
Accession NZ_CP048693
Organism Vibrio coralliilyticus OCN008

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag G3U99_RS14135 Protein ID WP_021458345.1
Coordinates 2938592..2938894 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag G3U99_RS14140 Protein ID WP_021458344.1
Coordinates 2938882..2939139 (-) Length 86 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G3U99_RS14090 2934155..2934637 - 483 WP_021458352.1 YbaK/EbsC family protein -
G3U99_RS14095 2934811..2935275 - 465 WP_021458351.1 DUF2846 domain-containing protein -
G3U99_RS26285 2935383..2935472 - 90 WP_072829120.1 DUF3265 domain-containing protein -
G3U99_RS14105 2936101..2936760 - 660 WP_021458349.1 hypothetical protein -
G3U99_RS14110 2936966..2937316 - 351 WP_021458348.1 cell envelope integrity protein TolA -
G3U99_RS14115 2937480..2937854 - 375 WP_021458347.1 hypothetical protein -
G3U99_RS14120 2937883..2937993 - 111 WP_200905126.1 DUF3265 domain-containing protein -
G3U99_RS14125 2937998..2938225 - 228 WP_031343357.1 hypothetical protein -
G3U99_RS14130 2938464..2938556 - 93 WP_207623562.1 DUF3265 domain-containing protein -
G3U99_RS14135 2938592..2938894 - 303 WP_021458345.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G3U99_RS14140 2938882..2939139 - 258 WP_021458344.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
G3U99_RS14145 2939329..2939682 - 354 WP_019277228.1 glyoxalase/bleomycin resistance/dioxygenase family protein -
G3U99_RS14150 2939829..2940086 - 258 WP_021458343.1 hypothetical protein -
G3U99_RS14155 2941022..2941115 - 94 Protein_2683 DUF3265 domain-containing protein -
G3U99_RS14160 2941252..2941476 + 225 WP_021458340.1 DUF3892 domain-containing protein -
G3U99_RS14165 2941661..2942143 - 483 WP_021458339.1 tetratricopeptide repeat protein -
G3U99_RS14170 2942250..2943026 - 777 WP_021458338.1 hypothetical protein -
G3U99_RS14175 2943180..2943617 - 438 WP_021458337.1 GIY-YIG nuclease family protein -
G3U99_RS14180 2943643..2943740 - 98 Protein_2688 DUF3265 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2903134..2946051 42917
- inside Integron - - 2907216..2944750 37534


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 101 a.a.        Molecular weight: 11568.46 Da        Isoelectric Point: 5.1879

>T149895 WP_021458345.1 NZ_CP048693:c2938894-2938592 [Vibrio coralliilyticus OCN008]
MAEIIWTEPALSDLNDIAEYIALENVVAAKQLVQTIFSKVERLEAFPESGRIPPELEHLSYREVVVNPCRVFYKQGGDKV
FILFVMRAERDLRKFLLSKQ

Download         Length: 303 bp

>T149895 NZ_CP064330:1388401-1388697 [Xylella fastidiosa subsp. fastidiosa]
ATGGTCGAACTCATCAAAACCAGCACTTTTGATGCTTGGATAAACAGCTTACGTGACCGCAAAGCAGCCGCCAGAATTCA
AGCGCGTCTTGATCGGCTCGCACTTGGCAATCCCGGCGACGTGAAGCCTGTGGGTGCTGGCATCTCAGAAATGAGGATCG
ACCATGGGCCCGGATATCGGATCTATTTTATGAAGCATGGTGCAGTACTGATTCTCTTACTTTGCGGTGGCGATAAATCG
TCACAAGTACGAGATATAGAGCAGGCTAAGGCACTGGCTGCACTGTGGAAGGATTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9634.15 Da        Isoelectric Point: 6.7269

>AT149895 WP_021458344.1 NZ_CP048693:c2939139-2938882 [Vibrio coralliilyticus OCN008]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALVDGKVVSHDEAKDKM
SKWLK

Download         Length: 258 bp

>AT149895 NZ_CP064330:1388701-1389006 [Xylella fastidiosa subsp. fastidiosa]
ATGAATAATGAGACTTTTAGTCGATACGACACCGCTGACTATCTCAAAACCGAAGAAGATATTGCGGCTTATATGGAAGC
CGTCATGGAAGAAGGTGGTAGGGATAATCCTGCTTTTATTGCACGGGCACTTGGTGCTGTCGCTCGTGCTCGTAATTTAA
GTCAGCTTGCTCGTGACGTTGGCATGTCCAGGCAAGGACTAGACAAGGCACTCTCTAACGACGGCAACCCAAGCTTCTCA
ACCATCTTAAAAGTGGCTAAAGCGCTTGGTTTACGGATGTCATTCACACCTTCCTCTATGAGTTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References