Detailed information of TA system TA149894

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 2914146..2914693
• Replicon: chromosome
• Accession: NZ_CP048693
• Organism: Vibrio coralliilyticus OCN008

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: G3U99_RS13920
• Protein ID: WP_021458100.1
• Coordinates: 2914146..2914448 (-)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A7H8DQL2
• Locus tag: G3U99_RS13925
• Protein ID: WP_021458101.1
• Coordinates: 2914436..2914693 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G3U99_RS13895	2909476..2909943	-	468	WP_021458092.1	hypothetical protein	-
G3U99_RS13900	2910102..2910488	-	387	WP_021458093.1	hypothetical protein	-
G3U99_RS13905	2912149..2912451	-	303	WP_021458096.1	DUF1330 domain-containing protein	-
G3U99_RS13910	2912605..2912988	-	384	WP_021458097.1	hypothetical protein	-
G3U99_RS13915	2913148..2913540	-	393	WP_021458098.1	hypothetical protein	-
G3U99_RS13920	2914146..2914448	-	303	WP_021458100.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
G3U99_RS13925	2914436..2914693	-	258	WP_021458101.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
G3U99_RS13930	2914891..2915223	-	333	WP_031343272.1	energy transducer TonB	-
G3U99_RS13935	2915335..2915865	-	531	WP_021458103.1	hypothetical protein	-
G3U99_RS13940	2916898..2916990	-	93	WP_080766692.1	DUF3265 domain-containing protein	-
G3U99_RS13945	2917018..2917756	-	739	Protein_2642	hypothetical protein	-
G3U99_RS13950	2918347..2918934	-	588	WP_021458105.1	hypothetical protein	-
G3U99_RS13955	2919095..2919379	-	285	WP_021458106.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2903134..2946051	42917
	-	inside	Integron	-	-	2907216..2944750	37534

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-86)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-69)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 11668.63 Da
• Isoelectric Point: 6.9806

>T149894 WP_021458100.1 NZ_CP048693:c2914448-2914146 [Vibrio coralliilyticus OCN008]
MAEIIWTEPALSDLNDIAEYIALENIVAAKQLVQTIFSKVERLQTFPESGRIPPELKHLSYREVVVNPCRVFYKQDGDKV
FILFVMRAERDLRKFLLSKQ

Nucleotide

• Length: 303 bp

>T149894 NZ_CP064330:1307367-1307648 [Xylella fastidiosa subsp. fastidiosa]
ATGCGGAGGATTAGCCAGACTGGCCAATTCAAGCGCGACTACAAGCGCGAAGCTAAGGGCCAGCATCGCGCCACGCTTGA
TGAGGAACTGATACACGTCTTGGAAGCCTTGACCTGTGATCATCCGTTGGAGCCACGCCACCACGATCACGCACTAACTG
GCGACTGGAAAGATCACCGTGATTGCCACATCAAACCCGACTTGGTACTGATATACCGGAAGCCCGACAACGAGACATTG
CAGCTCGTGCGCATTGGCTCACACAGCGAACTAGGTTTGTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9605.11 Da
• Isoelectric Point: 7.3177

>AT149894 WP_021458101.1 NZ_CP048693:c2914693-2914436 [Vibrio coralliilyticus OCN008]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVVSHDEAKNKM
SKWLK

Nucleotide

• Length: 258 bp

>AT149894 NZ_CP064330:1307117-1307380 [Xylella fastidiosa subsp. fastidiosa]
ATGTCTGCAAACGCAGTTGTCCGTGCCCGCGTTGACGCGCACATCAAAGAAGAAGCATCAACCGTGCTGGCGACGATGGG
CCTAAGCGTGTCTGATGCGTTCCGTATGATGCTGACCCGCATTGCCCGCGAGAAGGCGCTGCCGTTCGAGCCGCTGGTGC
CGAACGAAACTACCATCGCAGCCATGCGTGAAGCCCGTGCTGGTCACCTCAAGAGCTTTGATAGTATTGAGGCGCTCATG
GCGGACTTGCATGCGGAGGATTAG

Structures

Antitoxin

• AlphaFold DB: A0A7H8DQL2