Detailed information of TA system TA149880

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): NpoTA/ParE(toxin)
• Location: 1472268..1473383
• Replicon: chromosome
• Accession: NZ_CP048681
• Organism: Acinetobacter indicus strain Q186-3_T

Toxin (Protein)

• Gene name: NpoT
• Uniprot ID: V2U6R6
• Locus tag: G0030_RS06945
• Protein ID: WP_016658124.1
• Coordinates: 1472268..1472432 (-)
• Length: 55 a.a.

Antitoxin (Protein)

• Gene name: NpoA
• Uniprot ID: -
• Locus tag: G0030_RS06950
• Protein ID: WP_180182382.1
• Coordinates: 1472514..1473383 (-)
• Length: 290 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G0030_RS06930	1468246..1469268	+	1023	WP_180182380.1	ferredoxin reductase	-
G0030_RS06935	1469292..1470449	+	1158	WP_180182395.1	acyl-CoA desaturase	-
G0030_RS06940	1470750..1472168	+	1419	WP_180182381.1	iron-containing redox enzyme family protein	-
G0030_RS06945	1472268..1472432	-	165	WP_016658124.1	hypothetical protein	Toxin
G0030_RS06950	1472514..1473383	-	870	WP_180182382.1	SDR family oxidoreductase	Antitoxin
G0030_RS06955	1473486..1473725	-	240	WP_104471337.1	DUF2171 domain-containing protein	-
G0030_RS06960	1474384..1475625	+	1242	WP_016658127.1	MFS transporter	-
G0030_RS06965	1476063..1476350	+	288	WP_180182383.1	KGG domain-containing protein	-
G0030_RS06970	1476539..1476988	-	450	WP_180182384.1	cyanase	-
G0030_RS06975	1477281..1478090	+	810	WP_005178046.1	formate/nitrite transporter family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 55 a.a.
• Molecular weight: 6182.76 Da
• Isoelectric Point: 10.1466

>T149880 WP_016658124.1 NZ_CP048681:c1472432-1472268 [Acinetobacter indicus]
MSRGDKSAYTDKQKRQARHIIESEKERGHSEEEAERIGWSTVNKQDGGGKKKSH

Nucleotide

• Length: 165 bp

>T149880 NZ_CP048681:c1472432-1472268 [Acinetobacter indicus]
ATGTCTAGAGGTGATAAGTCGGCCTATACCGACAAGCAGAAACGTCAGGCCCGCCATATTATTGAATCGGAAAAAGAGCG
AGGCCATTCCGAAGAAGAAGCAGAACGCATTGGCTGGTCTACCGTCAATAAACAGGATGGCGGCGGTAAAAAGAAATCTC
ACTAA

Antitoxin

Protein

• Length: 290 a.a.
• Molecular weight: 31898.00 Da
• Isoelectric Point: 4.8531

>AT149880 WP_180182382.1 NZ_CP048681:c1473383-1472514 [Acinetobacter indicus]
MNHYPDSPSPQEKQEHQPGVQYKMTPEPEIIKSNYQGSQKLKDKVALITGGDSGIGRSVAVLFAREGANIIIPYLEEDQD
AQDTKRLVEQEGRQCLLIQCDMRQHAAVQQMVDLALQQFPHINILVNNAAVQYPQKTIEDINPEQLHKTFETNLYPLFYV
TQLLIPQMQAGDSIINTTSITSYQGHNELIDYASTKGAITAFTRSLSTNLLKNKTGIRVNGVAPGPIWTPLIPSSFDEEQ
LKGFGEDTPMGRMGQPSEVAPAYLFLASDEASYISGQVIHVNGGTIVNG

Nucleotide

• Length: 870 bp

>AT149880 NZ_CP048681:c1473383-1472514 [Acinetobacter indicus]
ATGAATCATTATCCTGACAGCCCATCTCCGCAAGAGAAACAGGAGCATCAGCCCGGTGTGCAATATAAAATGACGCCCGA
ACCTGAAATTATTAAAAGCAATTATCAGGGCAGTCAAAAACTCAAAGACAAGGTGGCCTTAATTACCGGCGGTGATAGCG
GCATCGGCCGCTCCGTGGCAGTGCTGTTTGCCCGCGAAGGTGCCAATATTATTATTCCCTATTTAGAAGAAGATCAGGAT
GCGCAAGACACCAAGCGACTGGTTGAGCAGGAAGGTCGTCAATGTCTGCTGATTCAGTGTGACATGCGCCAACATGCGGC
AGTGCAGCAGATGGTCGATCTGGCTTTGCAGCAGTTTCCGCATATTAATATTCTGGTCAATAATGCTGCTGTGCAATATC
CACAAAAAACCATTGAAGATATTAATCCCGAACAGCTGCATAAAACCTTTGAAACCAACCTCTACCCGCTGTTTTATGTG
ACCCAGCTGCTGATTCCTCAAATGCAGGCCGGTGACAGTATTATCAATACCACCAGTATCACCAGCTATCAGGGCCATAA
TGAGCTGATTGATTATGCCAGCACCAAAGGGGCAATTACCGCTTTTACCCGTAGCCTGTCGACCAACCTGCTAAAAAATA
AAACCGGGATTCGGGTGAATGGTGTCGCACCCGGCCCAATCTGGACGCCGTTAATTCCAAGCAGTTTTGATGAAGAACAG
CTAAAAGGTTTTGGTGAAGATACCCCCATGGGCCGCATGGGTCAGCCAAGTGAAGTTGCGCCGGCTTATCTGTTTTTAGC
CTCCGATGAAGCCAGCTATATTTCCGGTCAGGTGATTCATGTCAATGGCGGTACTATTGTCAATGGTTAA

Structures

Toxin

• AlphaFold DB: V2U6R6