Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 1454..1967 Replicon plasmid pYH12207-8
Accession NZ_CP048667
Organism Acinetobacter piscicola strain YH12207_T

Toxin (Protein)


Gene name yoeB Uniprot ID N8YGB2
Locus tag G0028_RS20915 Protein ID WP_000184943.1
Coordinates 1704..1967 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID N8ZW56
Locus tag G0028_RS20910 Protein ID WP_000557944.1
Coordinates 1454..1717 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G0028_RS20895 74..319 + 246 WP_000246756.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
G0028_RS20900 309..602 + 294 WP_000221358.1 type II toxin-antitoxin system RelE/ParE family toxin -
G0028_RS20905 731..1060 - 330 WP_000610966.1 four-helix bundle copper-binding protein -
G0028_RS20910 1454..1717 + 264 WP_000557944.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
G0028_RS20915 1704..1967 + 264 WP_000184943.1 Txe/YoeB family addiction module toxin Toxin
G0028_RS20920 2029..2331 - 303 WP_000110201.1 hypothetical protein -
G0028_RS20925 2543..4195 + 1653 WP_004870770.1 MobA/MobL family protein -
G0028_RS20930 4907..5848 + 942 WP_020846814.1 replication initiation protein -
G0028_RS20935 5845..6132 + 288 WP_004870774.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..8185 8185


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10649.09 Da        Isoelectric Point: 8.4866

>T149870 WP_000184943.1 NZ_CP048667:1704-1967 [Acinetobacter piscicola]
MTNRNVEWTDNAWDEYIYWQTQDKKILKRINTLIKECQRTPFEGTGKPEPLKANLSGFWSRRIDEKHRLVYEVTDERISI
IQCRFHY

Download         Length: 264 bp

>T149870 NZ_CP064325:c2454527-2454099 [Xylella fastidiosa subsp. multiplex]
ATGATTGTCTTGGATACCAATGTTGTTTCCGAAGCAATGAAACCCGAGCCGGATGCAGCAGTCCGAACCTGGCTCAACGA
GCAGATGAGCGTCACGTTGTACCTATCCAGTGTGACGTTATCTGAACTGTTGTTTGGAATCGCAGTGTTGCCCACAAGTA
AGCGCAAGGACATGTTGGCTCGTACCCTTGATGGCTTGCTTGATCTGTTCAATGAACGGGTGTTGCCGTTCGATACGGAC
GCGGCACGCCACTATGCTGAACTGGCAGTGAAAGCGAGAAACAATGGGCGCGGCTTTCCCACACCGGATGGCTATATCGC
GGCAATTGCTGCATCACGAGGTTACATAGTAGCTTCCCGCGACACCTCAGCCTATGAGTCAAGTGGTGTGCAAGTCATCA
ATCCGTGGCAATACAGCAAACAAACATAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9834.99 Da        Isoelectric Point: 5.0829

>AT149870 WP_000557944.1 NZ_CP048667:1454-1717 [Acinetobacter piscicola]
MHVFTYTDARNNLKSVLDKVIDDVDVAFITRKEGGHAVVMGQDHYDSLMETLYLLSSPNNASRLNESIAQLRAGKTKHRE
LIEDDES

Download         Length: 264 bp

>AT149870 NZ_CP064325:c2454782-2454528 [Xylella fastidiosa subsp. multiplex]
ATGGCCATGTTGACAGTGCGTAATTTGCCTGATGAAGTCCATCGCGCCTTGCGGGTTCGAGCCGCCACACACGGCCGCAG
TACAGAAGCGGAAGTACGTGAGATTTTAACGAACATAGTCAAGCCGGATGAGCGTGTTCGCATTGGCGATGCCTTGGCTA
TCCTGGGACGCGAGATCGGACTAAATAACGAGGATTTCACGACCTTTGATAAGGTGCGAGACAAGACGCAGGCCGAGCCG
ATGAGATTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6C0XPS2

Antitoxin

Source ID Structure
AlphaFold DB A0A6C0XPU2

References