Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 79480..79988 Replicon plasmid pYH12207-1
Accession NZ_CP048660
Organism Acinetobacter piscicola strain YH12207_T

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag G0028_RS19430 Protein ID WP_130075520.1
Coordinates 79480..79737 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag G0028_RS19435 Protein ID WP_130075519.1
Coordinates 79734..79988 (-) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G0028_RS19405 75061..76080 + 1020 WP_180048031.1 NADP-dependent oxidoreductase -
G0028_RS19410 76097..76735 + 639 WP_130075529.1 glutathione S-transferase -
G0028_RS19415 77146..77577 - 432 WP_111861135.1 PPC domain-containing protein -
G0028_RS19420 77678..78517 + 840 Protein_73 IS5 family transposase -
G0028_RS19425 78981..79248 - 268 Protein_74 DUF1778 domain-containing protein -
G0028_RS19430 79480..79737 - 258 WP_130075520.1 Txe/YoeB family addiction module toxin Toxin
G0028_RS19435 79734..79988 - 255 WP_130075519.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
G0028_RS19440 80248..81564 - 1317 WP_130075518.1 replication initiation protein RepM -
G0028_RS19445 82166..83138 + 973 Protein_78 IS3 family transposase -
G0028_RS19450 83230..83931 + 702 WP_180047887.1 IS1 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..184101 184101


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-84)

Antitoxin

(2-73)


Sequences


Toxin        


Download         Length: 86 a.a.        Molecular weight: 10108.58 Da        Isoelectric Point: 5.0038

>T149866 WP_130075520.1 NZ_CP048660:c79737-79480 [Acinetobacter piscicola]
MILSWTDEAWNDYLTWQSTDEQTLKRINLLIKDVIRSPFDGIGKPEPLKHNLSGLWSRQIDKINRLVYEVLDQQILIISC
CYHYD

Download         Length: 258 bp

>T149866 NZ_CP064325:1222398-1222679 [Xylella fastidiosa subsp. multiplex]
ATGATCAAAAGTTTCCGCCACAAAGGCATTCAACAATTCTTCCTTGTGGGATCAACCGCTGGTATCCAAACCAAACACGC
CGCCAAACTGCGTATCCAGCTCACCGCGTTGGAGAGTGCCAAGCGCCCCGAAGATATGAATGCTCCAGGCTGGAAACTGC
ACCCGCTAAAAGGCGCTGACTTAAAAGGTCATTGGTCCATCTGGGTGAATGGCAACTATCGCCTCACGTTTGCTTTTGAA
GGCGAAGACGCAATCTTGGTCGACTATCAGGATTACCACTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9373.66 Da        Isoelectric Point: 5.5427

>AT149866 WP_130075519.1 NZ_CP048660:c79988-79734 [Acinetobacter piscicola]
IKVVTYSYLRKNLANVLDGVIDDHSPVLVTRQNNQTAVLISLEDFNAYEETAYLMSSPANATHLMKSIAQAKLGKISQHE
LIEE

Download         Length: 255 bp

>AT149866 NZ_CP064325:1222690-1222965 [Xylella fastidiosa subsp. multiplex]
ATGAAACGTATGCACAATCCCGCACATCCAGGTGAAGTGTTGCGTGAGTATCTTGGTGATCTCACTGTGACCAATGCGGC
TGCAAAGCTAGGCGTCAGCCGTGTCGCTTTGTCGCGTATTCTCAATGGTACCAATGGCATCTCTGCCGATATGGCCCTTC
GCCTGGAAGATGCGCTTGGCACCAGTGCAGAGATGTGGGCAGCCATGCAGGCCAAGTATGACCTGTGGGTTGCTAGCCAG
CAGCCACGCCCGAAGATCACACGTCTTCATGTGTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References