Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/YoeB-RelB |
Location | 79480..79988 | Replicon | plasmid pYH12207-1 |
Accession | NZ_CP048660 | ||
Organism | Acinetobacter piscicola strain YH12207_T |
Toxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | G0028_RS19430 | Protein ID | WP_130075520.1 |
Coordinates | 79480..79737 (-) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | G0028_RS19435 | Protein ID | WP_130075519.1 |
Coordinates | 79734..79988 (-) | Length | 85 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
G0028_RS19405 | 75061..76080 | + | 1020 | WP_180048031.1 | NADP-dependent oxidoreductase | - |
G0028_RS19410 | 76097..76735 | + | 639 | WP_130075529.1 | glutathione S-transferase | - |
G0028_RS19415 | 77146..77577 | - | 432 | WP_111861135.1 | PPC domain-containing protein | - |
G0028_RS19420 | 77678..78517 | + | 840 | Protein_73 | IS5 family transposase | - |
G0028_RS19425 | 78981..79248 | - | 268 | Protein_74 | DUF1778 domain-containing protein | - |
G0028_RS19430 | 79480..79737 | - | 258 | WP_130075520.1 | Txe/YoeB family addiction module toxin | Toxin |
G0028_RS19435 | 79734..79988 | - | 255 | WP_130075519.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
G0028_RS19440 | 80248..81564 | - | 1317 | WP_130075518.1 | replication initiation protein RepM | - |
G0028_RS19445 | 82166..83138 | + | 973 | Protein_78 | IS3 family transposase | - |
G0028_RS19450 | 83230..83931 | + | 702 | WP_180047887.1 | IS1 family transposase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..184101 | 184101 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 10108.58 Da Isoelectric Point: 5.0038
>T149866 WP_130075520.1 NZ_CP048660:c79737-79480 [Acinetobacter piscicola]
MILSWTDEAWNDYLTWQSTDEQTLKRINLLIKDVIRSPFDGIGKPEPLKHNLSGLWSRQIDKINRLVYEVLDQQILIISC
CYHYD
MILSWTDEAWNDYLTWQSTDEQTLKRINLLIKDVIRSPFDGIGKPEPLKHNLSGLWSRQIDKINRLVYEVLDQQILIISC
CYHYD
Download Length: 258 bp
>T149866 NZ_CP064325:1222398-1222679 [Xylella fastidiosa subsp. multiplex]
ATGATCAAAAGTTTCCGCCACAAAGGCATTCAACAATTCTTCCTTGTGGGATCAACCGCTGGTATCCAAACCAAACACGC
CGCCAAACTGCGTATCCAGCTCACCGCGTTGGAGAGTGCCAAGCGCCCCGAAGATATGAATGCTCCAGGCTGGAAACTGC
ACCCGCTAAAAGGCGCTGACTTAAAAGGTCATTGGTCCATCTGGGTGAATGGCAACTATCGCCTCACGTTTGCTTTTGAA
GGCGAAGACGCAATCTTGGTCGACTATCAGGATTACCACTAG
ATGATCAAAAGTTTCCGCCACAAAGGCATTCAACAATTCTTCCTTGTGGGATCAACCGCTGGTATCCAAACCAAACACGC
CGCCAAACTGCGTATCCAGCTCACCGCGTTGGAGAGTGCCAAGCGCCCCGAAGATATGAATGCTCCAGGCTGGAAACTGC
ACCCGCTAAAAGGCGCTGACTTAAAAGGTCATTGGTCCATCTGGGTGAATGGCAACTATCGCCTCACGTTTGCTTTTGAA
GGCGAAGACGCAATCTTGGTCGACTATCAGGATTACCACTAG
Antitoxin
Download Length: 85 a.a. Molecular weight: 9373.66 Da Isoelectric Point: 5.5427
>AT149866 WP_130075519.1 NZ_CP048660:c79988-79734 [Acinetobacter piscicola]
IKVVTYSYLRKNLANVLDGVIDDHSPVLVTRQNNQTAVLISLEDFNAYEETAYLMSSPANATHLMKSIAQAKLGKISQHE
LIEE
IKVVTYSYLRKNLANVLDGVIDDHSPVLVTRQNNQTAVLISLEDFNAYEETAYLMSSPANATHLMKSIAQAKLGKISQHE
LIEE
Download Length: 255 bp
>AT149866 NZ_CP064325:1222690-1222965 [Xylella fastidiosa subsp. multiplex]
ATGAAACGTATGCACAATCCCGCACATCCAGGTGAAGTGTTGCGTGAGTATCTTGGTGATCTCACTGTGACCAATGCGGC
TGCAAAGCTAGGCGTCAGCCGTGTCGCTTTGTCGCGTATTCTCAATGGTACCAATGGCATCTCTGCCGATATGGCCCTTC
GCCTGGAAGATGCGCTTGGCACCAGTGCAGAGATGTGGGCAGCCATGCAGGCCAAGTATGACCTGTGGGTTGCTAGCCAG
CAGCCACGCCCGAAGATCACACGTCTTCATGTGTAA
ATGAAACGTATGCACAATCCCGCACATCCAGGTGAAGTGTTGCGTGAGTATCTTGGTGATCTCACTGTGACCAATGCGGC
TGCAAAGCTAGGCGTCAGCCGTGTCGCTTTGTCGCGTATTCTCAATGGTACCAATGGCATCTCTGCCGATATGGCCCTTC
GCCTGGAAGATGCGCTTGGCACCAGTGCAGAGATGTGGGCAGCCATGCAGGCCAAGTATGACCTGTGGGTTGCTAGCCAG
CAGCCACGCCCGAAGATCACACGTCTTCATGTGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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