Detailed information of TA system TA149857

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): NpoTA/ParE(toxin)
• Location: 71768..72883
• Replicon: chromosome
• Accession: NZ_CP048654
• Organism: Acinetobacter indicus strain C15_T

Toxin (Protein)

• Gene name: NpoT
• Uniprot ID: V2U6R6
• Locus tag: G0027_RS00315
• Protein ID: WP_016658124.1
• Coordinates: 71768..71932 (-)
• Length: 55 a.a.

Antitoxin (Protein)

• Gene name: NpoA
• Uniprot ID: -
• Locus tag: G0027_RS00320
• Protein ID: WP_180192059.1
• Coordinates: 72014..72883 (-)
• Length: 290 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G0027_RS00300	67745..68767	+	1023	WP_168399243.1	ferredoxin reductase	-
G0027_RS00305	68791..69948	+	1158	WP_171065080.1	acyl-CoA desaturase	-
G0027_RS00310	70250..71668	+	1419	WP_180192058.1	iron-containing redox enzyme family protein	-
G0027_RS00315	71768..71932	-	165	WP_016658124.1	hypothetical protein	Toxin
G0027_RS00320	72014..72883	-	870	WP_180192059.1	SDR family oxidoreductase	Antitoxin
G0027_RS00325	72986..73225	-	240	WP_104471337.1	DUF2171 domain-containing protein	-
G0027_RS00330	73884..75125	+	1242	WP_168384807.1	MFS transporter	-
G0027_RS00335	75564..75848	+	285	WP_160243174.1	KGG domain-containing protein	-
G0027_RS00340	76037..76486	-	450	WP_005178047.1	cyanase	-
G0027_RS00345	76779..77588	+	810	WP_005178046.1	formate/nitrite transporter family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 55 a.a.
• Molecular weight: 6182.76 Da
• Isoelectric Point: 10.1466

>T149857 WP_016658124.1 NZ_CP048654:c71932-71768 [Acinetobacter indicus]
MSRGDKSAYTDKQKRQARHIIESEKERGHSEEEAERIGWSTVNKQDGGGKKKSH

Nucleotide

• Length: 165 bp

>T149857 NZ_CP064314:1310478-1310780 [Lacticaseibacillus paracasei subsp. tolerans]
ATGTATAGTCTGGTTCCGACGCCTACATTTAAGCGCGATCTAAAACGACTCTCCAAGAAGCATTGGCCGATGGACGAACT
AAAGACGGCTGTTAATCTCCTAGCCGCTGGTACAAATGCTGAACTATTAAGCAAAAAGTATGCAGATCATGCCTTGTCCT
CAAGCAGCGAGTGGAAAGGATATCGTGAACTATATGTTGACGGCCCTCGTGGCGACTGGTTGCTAATCTATAAAATTGAG
CAGCAAGATCTTATTTTAACCCTAGTTAGAACCGGATCTCATCATAACCTTCTGGTTAAATAG

Antitoxin

Protein

• Length: 290 a.a.
• Molecular weight: 31903.00 Da
• Isoelectric Point: 4.9762

>AT149857 WP_180192059.1 NZ_CP048654:c72883-72014 [Acinetobacter indicus]
MHHYPDSPSPQEKQEHQPGVQYKMTPEPEIIKSNYQGSQKLKDKVALITGGDSGIGRSVAVLFAREGANIIIPYLEEDQD
AQDTKRLVEQEGRQCLLIQCDLRQHAAVQQMVDLALQQFPHINILVNNAAVQYPQKTIEDINPEQLHKTFETNLYPLFYV
TQLLIPQMQAGDSIINTTSITSYQGHNELIDYASTKGAITAFTRSLSTNLLKNKTGIRVNGVAPGPIWTPLIPSSFDEEQ
LKGFGEDTPMGRMGQPSEVAPAYLFLASDEASYISGQVIHVNGGTIVNG

Nucleotide

• Length: 870 bp

>AT149857 NZ_CP064314:1310216-1310485 [Lacticaseibacillus paracasei subsp. tolerans]
ATGGCAGCCACAAAGAAGGAAACTCGCTTGAATATTCGTGTTGATCCTGAATTAAAAAGTGCTGCTCAAATCGTAGCAAA
TGATATGGGCATCGACTTGACCGCAGCTGTTACGATGTTCATGACGAAAATGGTGAAAGATCACGCCCTCCCGTTTACCC
CAACAAGTCTACCAGTTGAAACCTTACAGGCGCTGAAAGAAGCAAAGCACCCAGAGCTGCTCAAAAAATACAGCACGCCT
GATGACATGTGGAGAGACTTGAATGTATAG

Structures

Toxin

• AlphaFold DB: V2U6R6