Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 239226..239911 Replicon plasmid p5
Accession NZ_CP048637
Organism Rhizobium oryzihabitans strain M15

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag G3A56_RS26810 Protein ID WP_164056733.1
Coordinates 239489..239911 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag G3A56_RS26805 Protein ID WP_164056725.1
Coordinates 239226..239492 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G3A56_RS26785 235105..236067 + 963 WP_082186230.1 IS110 family transposase -
G3A56_RS26790 236112..236864 + 753 WP_035228067.1 IS6 family transposase -
G3A56_RS26795 236920..237873 - 954 WP_164056724.1 DUF1403 family protein -
G3A56_RS26800 237998..239131 + 1134 WP_164056931.1 site-specific integrase -
G3A56_RS26805 239226..239492 + 267 WP_164056725.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
G3A56_RS26810 239489..239911 + 423 WP_164056733.1 type II toxin-antitoxin system VapC family toxin Toxin
G3A56_RS26815 239924..240592 + 669 WP_164056932.1 hypothetical protein -
G3A56_RS26820 240728..241615 + 888 WP_164056739.1 site-specific integrase -
G3A56_RS26825 241694..242161 - 468 WP_164056731.1 hypothetical protein -
G3A56_RS26830 242598..243557 - 960 WP_164056738.1 hypothetical protein -
G3A56_RS28610 243609..243785 - 177 WP_210255077.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..339368 339368


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-71)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15597.92 Da        Isoelectric Point: 4.7858

>T149788 WP_164056733.1 NZ_CP048637:239489-239911 [Rhizobium oryzihabitans]
MRLLLDTNVLSEVTKPRPNEDVLKWLHGLDEDRTFISIVSIAEIRRGVALMDSGRKRDALDEWLAHDLPQRFESRILPVE
GPVALAWGDLMALAKRSGRGLASMDGLIAATAVAYQLTLATRNTKDFEGFGIDIIDPWVD

Download         Length: 423 bp

>T149788 NZ_CP064246:331476-331844 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCAGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACTCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCGGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCGGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGCTTGCGCGGATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9729.00 Da        Isoelectric Point: 6.4672

>AT149788 WP_164056725.1 NZ_CP048637:239226-239492 [Rhizobium oryzihabitans]
MQASTHDDMSWTVAGAKAKLSEVMERAQLAPQTITRNGKPSVVVVSAEEWQKKTARRGSLAEFLLASPLRGADLDIERQH
DEPRDLSL

Download         Length: 267 bp

>AT149788 NZ_CP064246:331258-331479 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGACGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References