Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 5782..6467 Replicon plasmid p2
Accession NZ_CP048634
Organism Rhizobium oryzihabitans strain M15

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag G3A56_RS16790 Protein ID WP_164056733.1
Coordinates 5782..6204 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag G3A56_RS16795 Protein ID WP_164056725.1
Coordinates 6201..6467 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G3A56_RS28590 1907..2083 + 177 WP_210255077.1 hypothetical protein -
G3A56_RS16770 2135..3094 + 960 WP_164056738.1 hypothetical protein -
G3A56_RS16775 3531..3998 + 468 WP_164056731.1 hypothetical protein -
G3A56_RS16780 4077..4964 - 888 WP_164056739.1 site-specific integrase -
G3A56_RS16785 5100..5744 - 645 WP_164056732.1 hypothetical protein -
G3A56_RS16790 5782..6204 - 423 WP_164056733.1 type II toxin-antitoxin system VapC family toxin Toxin
G3A56_RS16795 6201..6467 - 267 WP_164056725.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
G3A56_RS16800 6561..7693 - 1133 Protein_8 site-specific integrase -
G3A56_RS16805 7818..8770 + 953 Protein_9 DUF1403 family protein -
G3A56_RS16810 8826..9578 - 753 WP_035228067.1 IS6 family transposase -
G3A56_RS16815 9623..10585 - 963 WP_164056734.1 hypothetical protein -
G3A56_RS16820 10592..11275 - 684 WP_130519741.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..16358 16358
- flank IS/Tn - - 8826..9578 752


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-71)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15597.92 Da        Isoelectric Point: 4.7858

>T149786 WP_164056733.1 NZ_CP048634:c6204-5782 [Rhizobium oryzihabitans]
MRLLLDTNVLSEVTKPRPNEDVLKWLHGLDEDRTFISIVSIAEIRRGVALMDSGRKRDALDEWLAHDLPQRFESRILPVE
GPVALAWGDLMALAKRSGRGLASMDGLIAATAVAYQLTLATRNTKDFEGFGIDIIDPWVD

Download         Length: 423 bp

>T149786 NZ_CP064243:c142891-142586 [Klebsiella pneumoniae]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTACAGAGTGACATTATTGACAC
GCCCGGGCGACGGATGGTGATCCCCCTGGCCAGTGCACGTCTGCTGTCAGATAAAGTCTCCCGTGAGCTTTACCCGGTGG
TGCATGTCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAAGAAGTG
GCTGATCTCAGTCACCGCGAAAATGACATCAAAAACGCCATTAACCTGATGTTCTGGGGAATATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9729.00 Da        Isoelectric Point: 6.4672

>AT149786 WP_164056725.1 NZ_CP048634:c6467-6201 [Rhizobium oryzihabitans]
MQASTHDDMSWTVAGAKAKLSEVMERAQLAPQTITRNGKPSVVVVSAEEWQKKTARRGSLAEFLLASPLRGADLDIERQH
DEPRDLSL

Download         Length: 267 bp

>AT149786 NZ_CP064243:c143111-142893 [Klebsiella pneumoniae]
ATGAAGCAGCGCATTACAGTCACCGTCGACAGTGACAGCTATCAGTTGCTCAAGGCATATGATGTCAATATCTCCGGTCT
GGTAAGCACCACCATGCAGAATGAAGCCCGTCGTCTGCGTGCCGAACGCTGGAAAGCGGAAAATCAGGAAGGGATGGCTG
AGGTCGCCCGGTTTATTGAAATGAACGGCTCTTTTGCCGATGAGAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References