Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 756155..756828 Replicon chromosome
Accession NZ_CP048630
Organism Ancylobacter pratisalsi strain DSM 102029

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag G3A50_RS03780 Protein ID WP_163074015.1
Coordinates 756406..756828 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag G3A50_RS03775 Protein ID WP_132036189.1
Coordinates 756155..756409 (+) Length 85 a.a.

Genomic Context

G3A50_RS03755G3A50_RS03760G3A50_RS03770G3A50_RS03775G3A50_RS03780G3A50_RS22365G3A50_RS03785G3A50_RS03790G3A50_RS03800G3A50_RS03805G3A50_RS03810G3A50_RS03815G3A50_RS03765G3A50_RS03795
Location: 751660..753723 (2064 bp)
Type: Others
Protein ID: WP_163074011.1
Location: 753793..754827 (1035 bp)
Type: Others
Protein ID: WP_163074012.1
Location: 755143..756069 (927 bp)
Type: Others
Protein ID: WP_163074014.1
Location: 756155..756409 (255 bp)
Type: Antitoxin
Protein ID: WP_132036189.1
Location: 756406..756828 (423 bp)
Type: Toxin
Protein ID: WP_163074015.1
Location: 757112..757279 (168 bp)
Type: Others
Protein ID: WP_170308624.1
Location: 757387..757827 (441 bp)
Type: Others
Protein ID: WP_163074016.1
Location: 758464..758790 (327 bp)
Type: Others
Protein ID: WP_163074017.1
Location: 759369..759635 (267 bp)
Type: Others
Protein ID: WP_149574633.1
Location: 760003..760485 (483 bp)
Type: Others
Protein ID: WP_210255274.1
Location: 760609..760890 (282 bp)
Type: Others
Protein ID: WP_012172356.1
Location: 760899..761786 (888 bp)
Type: Others
Protein ID: WP_163074019.1
Location: 754930..755112 (183 bp)
Type: Others
Protein ID: WP_163074013.1
Location: 758873..759121 (249 bp)
Type: Others
Protein ID: WP_163074018.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
G3A50_RS03755751660..753723+2064WP_163074011.1ParB/RepB/Spo0J family partition protein-
G3A50_RS03760753793..754827+1035WP_163074012.1toprim domain-containing protein-
G3A50_RS03765754930..755112-183WP_163074013.1hypothetical protein-
G3A50_RS03770755143..756069+927WP_163074014.1DUF2493 domain-containing protein-
G3A50_RS03775756155..756409+255WP_132036189.1plasmid stabilization proteinAntitoxin
G3A50_RS03780756406..756828+423WP_163074015.1type II toxin-antitoxin system VapC family toxinToxin
G3A50_RS22365757112..757279+168WP_170308624.1hypothetical protein-
G3A50_RS03785757387..757827+441WP_163074016.1hypothetical protein-
G3A50_RS03790758464..758790+327WP_163074017.1DUF736 domain-containing protein-
G3A50_RS03795758873..759121-249WP_163074018.1helix-turn-helix domain-containing protein-
G3A50_RS03800759369..759635+267WP_149574633.1DUF2285 domain-containing protein-
G3A50_RS03805760003..760485+483WP_210255274.1DUF2285 domain-containing protein-
G3A50_RS03810760609..760890+282WP_012172356.1helix-turn-helix domain-containing protein-
G3A50_RS03815760899..761786+888WP_163074019.1replication initiator protein A-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 14882.05 Da        Isoelectric Point: 4.5673

>T149780 WP_163074015.1 NZ_CP048630:756406-756828 [Ancylobacter pratisalsi]
MILLDTNVISEAMKPVPDDAVRAWLDEQVAETLYLSSVTIAELLFGIGALPAGKRKDKLTEALGGAMELFTDRVLPFDVA
AARRYADLAVKARAAGKGFPTPDGYIAAIADSRGFAVATRDTSAFDAAGVAVINPWNVER

Download         Length: 423 bp

>T149780 NZ_CP048630:756406-756828 [Ancylobacter pratisalsi]
ATGATTCTTCTCGACACCAATGTTATCTCGGAAGCGATGAAGCCCGTCCCCGACGACGCCGTGCGGGCGTGGCTCGACGA
GCAGGTGGCCGAGACGCTCTATCTCTCCAGCGTCACCATTGCCGAACTGTTGTTCGGCATCGGCGCGCTGCCAGCTGGCA
AGCGCAAGGACAAGCTCACGGAGGCCTTGGGCGGGGCGATGGAGCTGTTCACTGATCGCGTTCTGCCGTTCGATGTCGCT
GCCGCACGACGCTACGCCGACCTCGCGGTGAAAGCGCGGGCGGCTGGGAAGGGCTTTCCGACGCCCGATGGCTATATTGC
TGCGATTGCGGATTCCCGGGGCTTCGCTGTGGCCACGCGCGATACCAGTGCGTTCGACGCCGCCGGTGTGGCGGTCATCA
ATCCGTGGAATGTGGAACGCTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9365.60 Da        Isoelectric Point: 9.1399

>AT149780 WP_132036189.1 NZ_CP048630:756155-756409 [Ancylobacter pratisalsi]
MPAVTIRNLSEATHRALKVRAAQHGRSTEAEMRDILETAVRPDTRLRLGTALAERSRRLGLTNEDIDALSPARDRTPAEP
MSFE

Download         Length: 255 bp

>AT149780 NZ_CP048630:756155-756409 [Ancylobacter pratisalsi]
ATGCCCGCAGTGACGATCCGGAATCTCTCCGAGGCGACGCACCGCGCCTTGAAGGTGCGCGCGGCCCAGCATGGCCGCAG
CACCGAAGCCGAGATGCGCGACATCCTTGAGACCGCCGTTCGCCCTGACACGCGCCTCCGGCTCGGGACGGCGCTCGCGG
AGCGTAGCCGCCGCCTCGGCTTGACCAATGAGGACATCGACGCCCTCAGCCCGGCGCGAGATAGAACGCCCGCCGAGCCC
ATGAGCTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References