Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2782309..2782580 Replicon chromosome
Accession NZ_CP048609
Organism Escherichia coli strain STEFF_1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2782347..2782449 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2782309..2782580 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G3M66_RS13375 2779466..2780905 + 1440 WP_024179479.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
G3M66_RS13380 2781023..2781259 + 237 WP_001295499.1 YebV family protein -
G3M66_RS13385 2781364..2781555 + 192 WP_001296140.1 YebW family protein -
G3M66_RS13390 2781556..2782212 - 657 WP_000812752.1 protein-serine/threonine phosphatase -
- 2782309..2782580 + 272 - - Antitoxin
- 2782347..2782449 - 103 - - Toxin
G3M66_RS13395 2782608..2782949 - 342 WP_000976484.1 YebY family protein -
G3M66_RS13400 2782962..2783834 - 873 WP_000879323.1 copper homeostasis membrane protein CopD -
G3M66_RS13405 2783838..2784212 - 375 WP_000168737.1 CopC domain-containing protein YobA -
G3M66_RS13410 2784351..2784581 + 231 WP_000916763.1 DNA polymerase III subunit theta -
G3M66_RS13415 2784683..2785339 + 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
G3M66_RS13420 2785363..2786025 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T149742 NZ_CP048609:c2782449-2782347 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT149742 NZ_CP048609:2782309-2782580 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References