Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 2585029..2585627 Replicon chromosome
Accession NZ_CP048602
Organism Halomonas piezotolerans strain NBT06E8

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag GYM47_RS11825 Protein ID WP_153842731.1
Coordinates 2585029..2585328 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag GYM47_RS11830 Protein ID WP_044630743.1
Coordinates 2585325..2585627 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GYM47_RS11810 2580828..2583386 - 2559 WP_139526952.1 FtsX-like permease family protein -
GYM47_RS11815 2583379..2584194 - 816 WP_139526950.1 ABC transporter ATP-binding protein -
GYM47_RS11820 2584400..2584945 + 546 WP_139527241.1 arylesterase -
GYM47_RS11825 2585029..2585328 + 300 WP_153842731.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GYM47_RS11830 2585325..2585627 + 303 WP_044630743.1 putative addiction module antidote protein Antitoxin
GYM47_RS11835 2585707..2586420 + 714 WP_153842730.1 transglutaminase-like cysteine peptidase -
GYM47_RS11840 2586434..2588341 + 1908 WP_153842729.1 EAL domain-containing protein -
GYM47_RS11845 2588397..2588720 - 324 WP_139526945.1 tryptophan synthase subunit beta like protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(5-91)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11266.87 Da        Isoelectric Point: 10.4476

>T149652 WP_153842731.1 NZ_CP048602:2585029-2585328 [Halomonas piezotolerans]
MIAIKQTDTYRRWERKLRDSRTKALIAARIFRLANGLAGDVKPVGQGISELRIHHGPGYRVYFKQRGNELVILLCGGDKS
TQQNDIDTAQRLAAQWEES

Download         Length: 300 bp

>T149652 NZ_CP064208:c4627475-4626942 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCTGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10927.48 Da        Isoelectric Point: 4.3766

>AT149652 WP_044630743.1 NZ_CP048602:2585325-2585627 [Halomonas piezotolerans]
MSDKIYDYDPAAALENDEAIALFLADALETGDATYVAKAMGIVARAKGMTELARETGLSREQLYRSFSEQGNPTLKTMLA
VMRALGMDLTAKPHQEEPVM

Download         Length: 303 bp

>AT149652 NZ_CP064208:c4627752-4627486 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References