Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumAB/COG3657-dnstrm_HI1420 |
Location | 2087931..2088537 | Replicon | chromosome |
Accession | NZ_CP048589 | ||
Organism | Agrobacterium tumefaciens strain But002 |
Toxin (Protein)
Gene name | PumA | Uniprot ID | A0A822UZY8 |
Locus tag | FY129_RS10470 | Protein ID | WP_020011654.1 |
Coordinates | 2087931..2088227 (+) | Length | 99 a.a. |
Antitoxin (Protein)
Gene name | PumB | Uniprot ID | - |
Locus tag | FY129_RS10475 | Protein ID | WP_004429917.1 |
Coordinates | 2088232..2088537 (+) | Length | 102 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FY129_RS10435 (FY129_10365) | 2083525..2083872 | + | 348 | WP_004429958.1 | antibiotic biosynthesis monooxygenase | - |
FY129_RS10440 (FY129_10370) | 2083882..2084406 | + | 525 | WP_004429943.1 | heme utilization cystosolic carrier protein HutX | - |
FY129_RS10445 (FY129_10375) | 2084591..2084980 | + | 390 | WP_262576100.1 | hypothetical protein | - |
FY129_RS10450 (FY129_10380) | 2085133..2085672 | + | 540 | WP_004429935.1 | DUF2975 domain-containing protein | - |
FY129_RS10455 (FY129_10385) | 2085682..2085924 | + | 243 | WP_004429931.1 | helix-turn-helix transcriptional regulator | - |
FY129_RS10460 (FY129_10390) | 2086018..2086794 | + | 777 | WP_004429927.1 | YbaY family lipoprotein | - |
FY129_RS10465 (FY129_10395) | 2087001..2087885 | + | 885 | WP_112978057.1 | formyltetrahydrofolate deformylase | - |
FY129_RS10470 (FY129_10400) | 2087931..2088227 | + | 297 | WP_020011654.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
FY129_RS10475 (FY129_10405) | 2088232..2088537 | + | 306 | WP_004429917.1 | putative addiction module antidote protein | Antitoxin |
FY129_RS10480 (FY129_10410) | 2088551..2089945 | - | 1395 | WP_262576101.1 | sensor histidine kinase | - |
FY129_RS10485 (FY129_10415) | 2089942..2090622 | - | 681 | WP_003491888.1 | response regulator transcription factor | - |
FY129_RS10490 (FY129_10420) | 2090704..2091771 | + | 1068 | WP_051091653.1 | ABC transporter substrate-binding protein | - |
FY129_RS10495 (FY129_10425) | 2092197..2093141 | + | 945 | WP_020011659.1 | tripartite tricarboxylate transporter substrate binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 10888.61 Da Isoelectric Point: 10.2733
>T149635 WP_020011654.1 NZ_CP048589:2087931-2088227 [Agrobacterium tumefaciens]
MLTIRETSEFADWLAGLRDVQARARIARRIYRLADGNPGDVKPVGEGVSELRIDLGPGYRVYFVRHGDVVIILLCGGDKA
SQPRDIARAKKLARALKE
MLTIRETSEFADWLAGLRDVQARARIARRIYRLADGNPGDVKPVGEGVSELRIDLGPGYRVYFVRHGDVVIILLCGGDKA
SQPRDIARAKKLARALKE
Download Length: 297 bp
>T149635 NZ_CP064205:732163-732648 [Klebsiella pneumoniae]
ATGATCTCGGCACCAGAACCGCTTCATGCCGGGCATATTCTTACCCCGTTTTGCTGCGGTATAGATTCCATGGATCACTG
GCTGAAACAGCGGGCGATGAAAAATCAGGTTACTGGCGCATCCCGCACCTTTGTCTGCTGCGACGACGCGAAGGTGATGG
CTTACTACTCACTGGCTTCCAGCGCTGTGACGACAAATACTGCGCCGGGTCGTTTTCGCCGCAATATGCCTGACCCGATC
CCGGTTGTGGTACTGGGTCGTCTGGCGGTGGATAAATCACTACATGGGAAAGGTGTCGGGCGGGCGCTGGTACGTGATGC
CGGGCTGCGTGTGATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCCCTGTCGGATGAAGCACGGG
ATTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATTCGATGATGTTGATGGTGACGTTGAGGGATTTGGTTAAT
GCCTGA
ATGATCTCGGCACCAGAACCGCTTCATGCCGGGCATATTCTTACCCCGTTTTGCTGCGGTATAGATTCCATGGATCACTG
GCTGAAACAGCGGGCGATGAAAAATCAGGTTACTGGCGCATCCCGCACCTTTGTCTGCTGCGACGACGCGAAGGTGATGG
CTTACTACTCACTGGCTTCCAGCGCTGTGACGACAAATACTGCGCCGGGTCGTTTTCGCCGCAATATGCCTGACCCGATC
CCGGTTGTGGTACTGGGTCGTCTGGCGGTGGATAAATCACTACATGGGAAAGGTGTCGGGCGGGCGCTGGTACGTGATGC
CGGGCTGCGTGTGATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCCCTGTCGGATGAAGCACGGG
ATTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATTCGATGATGTTGATGGTGACGTTGAGGGATTTGGTTAAT
GCCTGA
Antitoxin
Download Length: 102 a.a. Molecular weight: 10592.90 Da Isoelectric Point: 4.5580
>AT149635 WP_004429917.1 NZ_CP048589:2088232-2088537 [Agrobacterium tumefaciens]
MPLVTRDYDAARYLDSDESLAAYIADATESGDAQELAHALGVVARAKGMTDLSRQTGLPRQTLYKALSGEGNPELATIAK
VADALGYRLSLVAKPPADTAA
MPLVTRDYDAARYLDSDESLAAYIADATESGDAQELAHALGVVARAKGMTDLSRQTGLPRQTLYKALSGEGNPELATIAK
VADALGYRLSLVAKPPADTAA
Download Length: 306 bp
>AT149635 NZ_CP064205:731873-732166 [Klebsiella pneumoniae]
ATGCCAGCCGCAAACAGCATGTCCATAAAACGCGAAACGTTAAATCTGCGCATTAAACCTGCCGAACGCGATCTTATTGA
TCGGGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAGGCCGCCCGCGCTGCCGCTGAGGAAGCGCTGA
TTGAGCAACGCATCATTATGGCCGATCCGCAGGCTTATCAGGAATTTCTCGCTCGTCTGGATCAGGCTCCTGCACCTAAT
GCCGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAACAGGAAGAATGA
ATGCCAGCCGCAAACAGCATGTCCATAAAACGCGAAACGTTAAATCTGCGCATTAAACCTGCCGAACGCGATCTTATTGA
TCGGGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAGGCCGCCCGCGCTGCCGCTGAGGAAGCGCTGA
TTGAGCAACGCATCATTATGGCCGATCCGCAGGCTTATCAGGAATTTCTCGCTCGTCTGGATCAGGCTCCTGCACCTAAT
GCCGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAACAGGAAGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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