Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 315779..316449 Replicon plasmid pAt1
Accession NZ_CP048586
Organism Agrobacterium pusense strain CC001

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FY130_RS24835 Protein ID WP_262622794.1
Coordinates 315779..316198 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID U4Q725
Locus tag FY130_RS24840 Protein ID WP_006699039.1
Coordinates 316195..316449 (-) Length 85 a.a.

Genomic Context

FY130_RS24810FY130_RS24815FY130_RS24820FY130_RS24825FY130_RS24830FY130_RS24845FY130_RS24860FY130_RS24865FY130_RS24875FY130_RS24835FY130_RS24840FY130_RS24850FY130_RS24855FY130_RS24870FY130_RS24880
Location: 310888..312078 (1191 bp)
Type: Others
Protein ID: WP_262622790.1
Location: 312183..312437 (255 bp)
Type: Others
Protein ID: WP_262622791.1
Location: 312566..313018 (453 bp)
Type: Others
Protein ID: WP_262622792.1
Location: 313031..314068 (1038 bp)
Type: Others
Protein ID: WP_107341275.1
Location: 314398..315339 (942 bp)
Type: Others
Protein ID: WP_262622793.1
Location: 316618..316848 (231 bp)
Type: Others
Protein ID: WP_128636328.1
Location: 318294..318617 (324 bp)
Type: Others
Protein ID: WP_262622796.1
Location: 318674..319006 (333 bp)
Type: Others
Protein ID: WP_262622797.1
Location: 319742..319906 (165 bp)
Type: Others
Protein ID: WP_262622798.1
Location: 315779..316198 (420 bp)
Type: Toxin
Protein ID: WP_262622794.1
Location: 316195..316449 (255 bp)
Type: Antitoxin
Protein ID: WP_006699039.1
Location: 316900..317406 (507 bp)
Type: Others
Protein ID: WP_262622795.1
Location: 317403..317888 (486 bp)
Type: Others
Protein ID: WP_025555388.1
Location: 319072..319350 (279 bp)
Type: Others
Protein ID: WP_006699033.1
Location: 320045..320371 (327 bp)
Type: Others
Protein ID: WP_262622799.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FY130_RS24810 (FY130_24600)310888..312078+1191WP_262622790.1DUF932 domain-containing protein-
FY130_RS24815 (FY130_24605)312183..312437+255WP_262622791.1DUF6117 family protein-
FY130_RS24820 (FY130_24610)312566..313018+453WP_262622792.1hypothetical protein-
FY130_RS24825 (FY130_24615)313031..314068+1038WP_107341275.1toprim domain-containing protein-
FY130_RS24830 (FY130_24620)314398..315339+942WP_262622793.1DUF2493 domain-containing protein-
FY130_RS24835 (FY130_24625)315779..316198-420WP_262622794.1type II toxin-antitoxin system VapC family toxinToxin
FY130_RS24840 (FY130_24630)316195..316449-255WP_006699039.1hypothetical proteinAntitoxin
FY130_RS24845 (FY130_24635)316618..316848+231WP_128636328.1hypothetical protein-
FY130_RS24850 (FY130_24640)316900..317406-507WP_262622795.1RES domain-containing protein-
FY130_RS24855 (FY130_24645)317403..317888-486WP_025555388.1DUF2384 domain-containing protein-
FY130_RS24860 (FY130_24650)318294..318617+324WP_262622796.1DUF736 family protein-
FY130_RS24865 (FY130_24655)318674..319006+333WP_262622797.1hypothetical protein-
FY130_RS24870 (FY130_24660)319072..319350-279WP_006699033.1HU family DNA-binding protein-
FY130_RS24875319742..319906+165WP_262622798.1hypothetical protein-
FY130_RS24880 (FY130_24665)320045..320371-327WP_262622799.1WGR domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid-gmd / htpB1..426589426589


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15032.12 Da        Isoelectric Point: 4.8728

>T149631 WP_262622794.1 NZ_CP048586:c316198-315779 [Agrobacterium pusense]
MILLDTNVVSETMKPFPSQMVQRWLDEQAAETLHLSSITIAEAIFGIRTMPDGQRKQRLAEALDVWIGLFEGRILPFDLD
AAKHYANLGSSARASGKGFPTPDGYIAAIAASKGFAVATRDASAFHAAGLEVIDPWTAE

Download         Length: 420 bp

>T149631 NZ_CP064202:6-293 [Acinetobacter baumannii]
ATGGAACAGTATTTTGAATGGGATGAGGCTAAGAATCGAAAGAATCAGAAAAAGCATGATATCTCTTTCGAAACTGCAAG
CCTTGTTTTTGAAGATCCATTACGGATCTCAATCCAAGACAGACATACCAATGGTGAAGAACGTTGGCAAACCATTGGAC
GAGTTAAAGGCGTACTAATGTTATTGGTGGCTCACACCATTTTTGATGAAGATGACTGTGAAATCATCCGAATCATTAGT
GCAAGGCAAGTCACTAAAGCGGAGCGAAACAAATATGAGCATGGTTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9374.65 Da        Isoelectric Point: 6.7270

>AT149631 WP_006699039.1 NZ_CP048586:c316449-316195 [Agrobacterium pusense]
VPAVTIRNIPEETHRAIKIRAAQHGRSAEAEMRDILEMAVRPATRLRLGTALAEASRRIGLTNEDVDALEQTFDRTPAHP
MSFE

Download         Length: 255 bp

>AT149631 NZ_CP064202:280-594 [Acinetobacter baumannii]
ATGAGCATGGTTAGATACTCACACAAAGAGCTGAATGAGAAATTTGGTGAGAAGCAAGATGCTGAAATTCAACGCTTGCT
TGCTAAAGGCACGGTTCCTGATGATCAGCTAGATCTATCAGATATTCCTGAAATTACAGACTGGAGCAATGCTGTACGCC
AAAATCAATTTTACCGCCCAGTAAAGCAACAAACTTCAATTCGGTTAGATGCTGATGTACTTGCTTGGTTCAAAGCACAA
GGCAAAGGTTATCAAACACGTATGAATGAAATTTTACGAGATGCTATGCTAAAAGAATTAAAAAATCATCAATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBU4Q725

References