Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 80535..81115 Replicon plasmid pAt1
Accession NZ_CP048586
Organism Agrobacterium pusense strain CC001

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FY130_RS23635 Protein ID WP_262622951.1
Coordinates 80535..80918 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FY130_RS23640 Protein ID WP_262622952.1
Coordinates 80915..81115 (-) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FY130_RS23605 (FY130_23430) 76201..76809 - 609 WP_111815102.1 NAD(P)H:quinone oxidoreductase -
FY130_RS23610 (FY130_23435) 76980..77576 - 597 WP_111815104.1 NADPH-dependent F420 reductase -
FY130_RS23615 (FY130_23440) 77603..78499 - 897 WP_262622949.1 pirin family protein -
FY130_RS23620 (FY130_23445) 78600..79514 + 915 WP_262622950.1 LysR family transcriptional regulator -
FY130_RS23625 (FY130_23450) 79636..80067 - 432 WP_044460075.1 type II toxin-antitoxin system VapC family toxin -
FY130_RS23630 (FY130_23455) 80067..80366 - 300 WP_082055481.1 hypothetical protein -
FY130_RS23635 (FY130_23460) 80535..80918 - 384 WP_262622951.1 type II toxin-antitoxin system VapC family toxin Toxin
FY130_RS23640 (FY130_23465) 80915..81115 - 201 WP_262622952.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
FY130_RS23645 (FY130_23470) 81310..83670 - 2361 WP_262622953.1 hypothetical protein -
FY130_RS23650 (FY130_23475) 83957..84397 - 441 WP_234942636.1 PIN domain-containing protein -
FY130_RS23655 (FY130_23480) 84387..84833 - 447 WP_262622954.1 DNA-binding protein -
FY130_RS23660 (FY130_23485) 85012..85494 - 483 Protein_91 LysR substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - gmd / htpB 1..426589 426589


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14102.30 Da        Isoelectric Point: 6.9166

>T149628 WP_262622951.1 NZ_CP048586:c80918-80535 [Agrobacterium pusense]
VILVDSSIWIDHFRHVEPELVKIIGDDQLLCHPFVVGELALGSLRERDAVLAFLTAQREAVVATHAEVMTVIDRHSIFSM
GIGYTDAHLLTSTLLDRRSSLWTRDKRLAAAARKAGAALYLSPHIPH

Download         Length: 384 bp

>T149628 NZ_CP064193:6632-6919 [Acinetobacter baumannii]
ATGGAACAGTATTTTGAATGGGATGAGGCTAAGAATCGAAAGAATCAGAAAAAGCATGATATCTCTTTCGAAACTGCAAG
CCTTGTTTTTGAAGATCCATTACGGATCTCAATCCAAGACAGACATACCAATGGTGAAGAACGTTGGCAAACCATTGGAC
GAGTTAAAGGCGTACTAATGTTATTGGTGGCTCACACCATTTTTGATGAAGATGACTGTGAAATCATCCGAATCATTAGT
GCAAGGCAAGTCACTAAAGCGGAGCGAAACAAATATGAGCATGGTTAG

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7195.35 Da        Isoelectric Point: 11.4483

>AT149628 WP_262622952.1 NZ_CP048586:c81115-80915 [Agrobacterium pusense]
MRSTINLDDSLMERAKSLTGTKETAALVRQALETLVRVESGKRLIALGGTMPEAEAAPRRRSGVRK

Download         Length: 201 bp

>AT149628 NZ_CP064193:6906-7220 [Acinetobacter baumannii]
ATGAGCATGGTTAGATACTCACACAAAGAGCTGAATGAGAAATTTGGTGAGAAGCAAGATGCTGAAATTCAACGCTTGCT
TGCTAAAGGCACGGTTCCTGATGATCAGCTAGATCTATCAGATATTCCTGAAATTACAGACTGGAGCAATGCTGTACGCC
AAAATCAATTTTACCGCCCAGTAAAGCAACAAACTTCAATTCGGTTAGATGCTGATGTACTTGCTTGGTTCAAAGCACAA
GGCAAAGGTTATCAAACACGTATGAATGAAATTTTACGAGATGCTATGCTAAAAGAATTAAAAAATCATCAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References