Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2058939..2059545 Replicon chromosome
Accession NZ_CP048584
Organism Agrobacterium pusense strain CC001

Toxin (Protein)


Gene name PumA Uniprot ID A0A7W4TY99
Locus tag FY130_RS10260 Protein ID WP_004443439.1
Coordinates 2058939..2059235 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag FY130_RS10265 Protein ID WP_004443440.1
Coordinates 2059240..2059545 (+) Length 102 a.a.

Genomic Context

FY130_RS10240FY130_RS10245FY130_RS10250FY130_RS10255FY130_RS10260FY130_RS10265FY130_RS10280FY130_RS10285FY130_RS10235FY130_RS10270FY130_RS10275
Location: 2055808..2056155 (348 bp)
Type: Others
Protein ID: WP_004429958.1
Location: 2056165..2056689 (525 bp)
Type: Others
Protein ID: WP_004443430.1
Location: 2057025..2057801 (777 bp)
Type: Others
Protein ID: WP_004443433.1
Location: 2058009..2058893 (885 bp)
Type: Others
Protein ID: WP_004443436.1
Location: 2058939..2059235 (297 bp)
Type: Toxin
Protein ID: WP_004443439.1
Location: 2059240..2059545 (306 bp)
Type: Antitoxin
Protein ID: WP_004443440.1
Location: 2061710..2062777 (1068 bp)
Type: Others
Protein ID: WP_006700422.1
Location: 2063128..2064072 (945 bp)
Type: Others
Protein ID: WP_004443448.1
Location: 2054728..2055621 (894 bp)
Type: Others
Protein ID: WP_004443429.1
Location: 2059557..2060951 (1395 bp)
Type: Others
Protein ID: WP_004443442.1
Location: 2060948..2061628 (681 bp)
Type: Others
Protein ID: WP_004443444.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FY130_RS10235 (FY130_10150)2054728..2055621-894WP_004443429.1hemin ABC transporter substrate-binding protein-
FY130_RS10240 (FY130_10155)2055808..2056155+348WP_004429958.1antibiotic biosynthesis monooxygenase-
FY130_RS10245 (FY130_10160)2056165..2056689+525WP_004443430.1heme utilization cystosolic carrier protein HutX-
FY130_RS10250 (FY130_10165)2057025..2057801+777WP_004443433.1YbaY family lipoprotein-
FY130_RS10255 (FY130_10170)2058009..2058893+885WP_004443436.1formyltetrahydrofolate deformylase-
FY130_RS10260 (FY130_10175)2058939..2059235+297WP_004443439.1type II toxin-antitoxin system RelE/ParE family toxinToxin
FY130_RS10265 (FY130_10180)2059240..2059545+306WP_004443440.1putative addiction module antidote proteinAntitoxin
FY130_RS10270 (FY130_10185)2059557..2060951-1395WP_004443442.1sensor histidine kinase-
FY130_RS10275 (FY130_10190)2060948..2061628-681WP_004443444.1response regulator transcription factor-
FY130_RS10280 (FY130_10195)2061710..2062777+1068WP_006700422.1ABC transporter substrate-binding protein-
FY130_RS10285 (FY130_10200)2063128..2064072+945WP_004443448.1tripartite tricarboxylate transporter substrate binding protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(47-90)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10923.61 Da        Isoelectric Point: 10.2206

>T149626 WP_004443439.1 NZ_CP048584:2058939-2059235 [Agrobacterium pusense]
MLTIRETSEFADWLAGLRDLQARARIARRIYRLADGNPGDVKPVGEGVSELRIDFGPGYRVYFFRNGDVVIILLCGGDKA
SQSRDIAKAKKLARALKE

Download         Length: 297 bp

>T149626 NZ_CP064192:224305-224559 [Saccharothrix sp. 6-C]
GTGAGGCTCGTCTTCGAAGAGCAGGGCTGGGAGGACTACACGTCCTGGCTCAAGAACGACCGCAAGATGCTCGCCCGGGT
CAACAAGCTCATCGAGGACGCGCTCCGGGATCCGTTCACCGGGATCGGCAAACCCGAGCCGCTGAAGTACCACCTGCCCG
GCGCTTGGTCGAGGCGGATCGATGACGAACACCGCCTCGTCTACCTGGTCGTCGACGACCAGGTCATCGTGCTCGCCGCT
CGGTACCACTACTGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10547.84 Da        Isoelectric Point: 4.5580

>AT149626 WP_004443440.1 NZ_CP048584:2059240-2059545 [Agrobacterium pusense]
MPLVTRDYDAARYLDSDEALAAYIADATENGDAQELAHALGVVARAKGITDLSRQTGLPRQTLYKALSGEGNPELATIAK
VADALGYKLSLVAKSPADTAA

Download         Length: 306 bp

>AT149626 NZ_CP064192:224027-224308 [Saccharothrix sp. 6-C]
ATGTCGATTACCGCGAGTGAGGCCCGCAAGGCTCTCTTCCCGCTGATCAAGCAGGTCAACGAAGACCACGAGGCCATCGA
GATCGTCTCCAAGCACGGCAATGCCGTGCTCGTCTCGGCCGAGGACTACGCCGCGCTCCGTGAAGGCTCTTACCTCTTGC
GCTCGCCCGCCAACGCGCGTCGCCTGCTCAAGGCCTACGAGAACGCTCTCGGCGGCGTCGGGCTCTCGGCGCGCGAGTTG
ATCGACTCTGAGGCCGCGGACGCGAAAGCCGGAGCCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A7W4TY99

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References