149625

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 490681..491275 Replicon chromosome
Accession NZ_CP048584
Organism Agrobacterium pusense strain CC001

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FY130_RS02360 Protein ID WP_004440489.1
Coordinates 490961..491275 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FY130_RS02355 Protein ID WP_004440487.1
Coordinates 490681..490980 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FY130_RS02330 (FY130_02330) 485816..486814 + 999 WP_004440476.1 asparaginase -
FY130_RS02335 (FY130_02335) 486949..487569 + 621 WP_004440479.1 glutathione S-transferase family protein -
FY130_RS02340 (FY130_02340) 487723..488382 - 660 WP_004440482.1 glutathione S-transferase family protein -
FY130_RS02345 (FY130_02345) 488465..488980 - 516 WP_004440484.1 MarR family transcriptional regulator -
FY130_RS02350 (FY130_02350) 489122..490651 + 1530 WP_004440486.1 MDR family MFS transporter -
FY130_RS02355 (FY130_02355) 490681..490980 - 300 WP_004440487.1 putative addiction module antidote protein Antitoxin
FY130_RS02360 (FY130_02360) 490961..491275 - 315 WP_004440489.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FY130_RS02365 (FY130_02365) 491515..492525 + 1011 WP_034496274.1 ligase-associated DNA damage response exonuclease -
FY130_RS02370 (FY130_02370) 492527..494152 + 1626 WP_004440496.1 cisplatin damage response ATP-dependent DNA ligase -
FY130_RS02375 (FY130_02375) 494324..495289 + 966 WP_034495910.1 prolyl oligopeptidase family serine peptidase -
FY130_RS02380 (FY130_02380) 495325..496107 - 783 WP_004440500.1 glycosyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-95)

Antitoxin

Uncharacterized protein HI1420

(3-97)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11746.36 Da        Isoelectric Point: 9.5802

>T149625 WP_004440489.1 NZ_CP048584:c491275-490961 [Agrobacterium pusense]
MNDFEKSAEFDEWLKALKDRTGKARILHRLTAAEHGNFGDCEPVGGGVSEMRIHCGPGYRVYFTRIGKRVYFLLVGGDKS
SQKRDIKRAVEMAQTIGRNDRDAV

Download         Length: 315 bp

>T149625 NZ_CP064191:369385-369678 [Rhizobium sp. 007]
ATGGCTGAAAAGATCATGGATTTCGACGTTGCCGATATGCTCGATTCCGACGAGGCAATCGAGGCGTTCCTGACGGAAGC
CATGGAGACCGGCGACGCAAAGTTTATCGCCTCCGCCCTTGGCGTCGTTGCCCGCGCGAAGGGCATGAGCAAGATTGCCC
GCGAAACCGGCCTTGCTCGCGAACACCTCTATAAGTCGCTCAGCGAGGATGGAAATCCGACGCTCGGAACGACGCTGGCC
GTTATGAAGGCCTTGGGCTTCCAGCTCGCCACAAAGCATCATGTCGCGGCCTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10755.25 Da        Isoelectric Point: 5.6863

>AT149625 WP_004440487.1 NZ_CP048584:c490980-490681 [Agrobacterium pusense]
MTVTQFSKFDVSDYLNSDEAMLEYLAVAMEDENPDVFIAALGAVARARGMSHVADAAGLGRESLYKALKPGSKLRYETVQ
KILHSLGFRLAVEKSSNAA

Download         Length: 300 bp

>AT149625 NZ_CP064191:369087-369392 [Rhizobium sp. 007]
ATGATAGAGCTGAAGCAAACCGCCACCTTTCAGAAGTGGCACCGCAAATTGAAGGACGGCAAGGCCAAAGCGGCGATCGC
TATGCGCCTTCACCGTCTGGAAATGGGAAATCCCGGCGATGTCGCCCCCGTTGGCGAGGGCATCAGCGAACTACGCATTC
ACTACGGCCCCGGCTATCGCGTCTATTTCCAGCAGCGGGGCAATGTCATCGTCGTCCTTTTGTGCGGCGGGGACAAGAGA
ACACAAGGAACCGATATCCAGACGGCAAAGCAACTGGCCGCTGAGTGGAGTGAAGATGATGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References