Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 540806..541400 Replicon chromosome
Accession NZ_CP048569
Organism Agrobacterium tumefaciens strain Gle001

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FY132_RS02710 Protein ID WP_080865974.1
Coordinates 541086..541400 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FY132_RS02705 Protein ID WP_080865973.1
Coordinates 540806..541105 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FY132_RS02680 (FY132_02675) 535994..536992 + 999 WP_060723902.1 asparaginase -
FY132_RS02685 (FY132_02680) 537127..537747 + 621 WP_003508980.1 glutathione S-transferase family protein -
FY132_RS02690 (FY132_02685) 537841..538500 - 660 WP_003508979.1 glutathione S-transferase family protein -
FY132_RS02695 (FY132_02690) 538583..539098 - 516 WP_099085580.1 MarR family transcriptional regulator -
FY132_RS02700 (FY132_02695) 539240..540769 + 1530 WP_060723904.1 MDR family MFS transporter -
FY132_RS02705 (FY132_02700) 540806..541105 - 300 WP_080865973.1 putative addiction module antidote protein Antitoxin
FY132_RS02710 (FY132_02705) 541086..541400 - 315 WP_080865974.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FY132_RS02715 (FY132_02710) 541631..542647 + 1017 WP_163117905.1 ligase-associated DNA damage response exonuclease -
FY132_RS02720 (FY132_02715) 542649..544274 + 1626 WP_099085579.1 cisplatin damage response ATP-dependent DNA ligase -
FY132_RS02725 (FY132_02720) 544449..545414 + 966 WP_020813204.1 alpha/beta fold hydrolase -
FY132_RS02730 (FY132_02725) 545453..546235 - 783 WP_003508963.1 glycosyltransferase family 32 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-95)

Antitoxin

Uncharacterized protein HI1420

(6-97)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11772.48 Da        Isoelectric Point: 10.3857

>T149624 WP_080865974.1 NZ_CP048569:c541400-541086 [Agrobacterium tumefaciens]
MNSFQKSAEFDEWLKVLKDRAGKVRILHRLTAAEHGNFGDCAPVGEGVSEMRIHFGPGYRVYFTRVGKRVYFLLVGGDKS
SQRRDIKRAIEMAQTIGRDGRDGI

Download         Length: 315 bp

>T149624 NZ_CP064191:369087-369392 [Rhizobium sp. 007]
ATGATAGAGCTGAAGCAAACCGCCACCTTTCAGAAGTGGCACCGCAAATTGAAGGACGGCAAGGCCAAAGCGGCGATCGC
TATGCGCCTTCACCGTCTGGAAATGGGAAATCCCGGCGATGTCGCCCCCGTTGGCGAGGGCATCAGCGAACTACGCATTC
ACTACGGCCCCGGCTATCGCGTCTATTTCCAGCAGCGGGGCAATGTCATCGTCGTCCTTTTGTGCGGCGGGGACAAGAGA
ACACAAGGAACCGATATCCAGACGGCAAAGCAACTGGCCGCTGAGTGGAGTGAAGATGATGGCTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10765.29 Da        Isoelectric Point: 4.8307

>AT149624 WP_080865973.1 NZ_CP048569:c541105-540806 [Agrobacterium tumefaciens]
MAVTEFSKFDVSDYLDSDEAMIEFLAIAMEDENPDVFIGALGAVAKARGMSHIADASGLGRESLYKALRPGSKLRYETVQ
RVLHALGFRLAVEKSLNAA

Download         Length: 300 bp

>AT149624 NZ_CP064191:369385-369678 [Rhizobium sp. 007]
ATGGCTGAAAAGATCATGGATTTCGACGTTGCCGATATGCTCGATTCCGACGAGGCAATCGAGGCGTTCCTGACGGAAGC
CATGGAGACCGGCGACGCAAAGTTTATCGCCTCCGCCCTTGGCGTCGTTGCCCGCGCGAAGGGCATGAGCAAGATTGCCC
GCGAAACCGGCCTTGCTCGCGAACACCTCTATAAGTCGCTCAGCGAGGATGGAAATCCGACGCTCGGAACGACGCTGGCC
GTTATGAAGGCCTTGGGCTTCCAGCTCGCCACAAAGCATCATGTCGCGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References