Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pasABC/RelE-HTH |
| Location | 398828..399314 | Replicon | chromosome |
| Accession | NZ_CP048564 | ||
| Organism | Agrobacterium tumefaciens strain Gle002 | ||
Toxin (Protein)
| Gene name | pasB | Uniprot ID | - |
| Locus tag | FY133_RS01930 | Protein ID | WP_262514254.1 |
| Coordinates | 398828..399097 (-) | Length | 90 a.a. |
Antitoxin (Protein)
| Gene name | pasA | Uniprot ID | A0A822V377 |
| Locus tag | FY133_RS01935 | Protein ID | WP_003503188.1 |
| Coordinates | 399081..399314 (-) | Length | 78 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FY133_RS01895 (FY133_01895) | 393850..394479 | + | 630 | WP_020010519.1 | DNA-3-methyladenine glycosylase I | - |
| FY133_RS01900 (FY133_01900) | 394476..394922 | + | 447 | WP_080865875.1 | hypothetical protein | - |
| FY133_RS01905 (FY133_01905) | 394938..395981 | - | 1044 | WP_065694890.1 | YeiH family protein | - |
| FY133_RS01910 (FY133_01910) | 396063..396980 | + | 918 | WP_026363679.1 | LysR substrate-binding domain-containing protein | - |
| FY133_RS01915 (FY133_01915) | 397191..397565 | - | 375 | WP_262514251.1 | DUF305 domain-containing protein | - |
| FY133_RS01920 (FY133_01920) | 397623..398015 | - | 393 | WP_262514252.1 | hypothetical protein | - |
| FY133_RS01925 (FY133_01925) | 398057..398821 | - | 765 | WP_262514253.1 | hypothetical protein | - |
| FY133_RS01930 (FY133_01930) | 398828..399097 | - | 270 | WP_262514254.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| FY133_RS01935 (FY133_01935) | 399081..399314 | - | 234 | WP_003503188.1 | DUF6290 family protein | Antitoxin |
| FY133_RS01940 (FY133_01940) | 399472..400995 | + | 1524 | WP_262514255.1 | histidine--tRNA ligase | - |
| FY133_RS01945 (FY133_01945) | 401000..401368 | + | 369 | WP_020010527.1 | VOC family protein | - |
| FY133_RS01950 (FY133_01950) | 401385..402512 | + | 1128 | WP_262514256.1 | ATP phosphoribosyltransferase regulatory subunit | - |
| FY133_RS01955 (FY133_01955) | 402509..403201 | + | 693 | WP_003503184.1 | ATP phosphoribosyltransferase | - |
| FY133_RS01960 (FY133_01960) | 403266..403712 | - | 447 | WP_003503183.1 | DoxX family protein | - |
| FY133_RS01965 (FY133_01965) | 403869..404303 | - | 435 | WP_003503182.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 90 a.a. Molecular weight: 10283.91 Da Isoelectric Point: 10.8712
>T149618 WP_262514254.1 NZ_CP048564:c399097-398828 [Agrobacterium tumefaciens]
MIWKIEFQRAAVKQLGALTKSDANRIVSFLTGRIARDGNPRRTGAALQGSELGNFWRYRVGDYRIICDIQDHKLVVLVVE
IGHRREIYR
MIWKIEFQRAAVKQLGALTKSDANRIVSFLTGRIARDGNPRRTGAALQGSELGNFWRYRVGDYRIICDIQDHKLVVLVVE
IGHRREIYR
Download Length: 270 bp
>T149618 NZ_CP064188:1074045-1074551 [Rhizobium sp. 007]
ATGCCTGAGACCGTCGTGCATCTATGGCGCGCCTTCGTTCCACGATGGGCCCATGCGCCGCTTTCTGGGGAGGGCGCCAG
CCGTTTTGGTGGCCGGTGGAATCGGGTGGGTGCCCCGACCATCTATGCGGCCTGCGAGCTGTCCACGGCCTGGGCCGAAT
ATAACCAGGGCTTTGTTCAGCACCCGGCGATGATCGTGCAATTGGAACTCAAAGGGGCGCGCCTCGCGGACACGACCGAC
CAGATGCTTCTTCGAAAGTTTGACGTTACTGCGGATATCCATCGTTGCGAATGGCGGATGCTGATGGATGAAAGCAAGGT
GCCGGCAACCCACCACCTGCGCGAACGTCTGATTGCATCGCGATATCATGGCGCGATCTATCCATCTTTCATGTCGCTCG
GCGGCACATGCGTCGCGCTGTGGGAATGGAATATGCCGGGTGCACCGGAGCTTCGCGCAATCGATCCAGAGGGTCGACTG
CCCAAATCACCGGCCTCCTGGTTGTAG
ATGCCTGAGACCGTCGTGCATCTATGGCGCGCCTTCGTTCCACGATGGGCCCATGCGCCGCTTTCTGGGGAGGGCGCCAG
CCGTTTTGGTGGCCGGTGGAATCGGGTGGGTGCCCCGACCATCTATGCGGCCTGCGAGCTGTCCACGGCCTGGGCCGAAT
ATAACCAGGGCTTTGTTCAGCACCCGGCGATGATCGTGCAATTGGAACTCAAAGGGGCGCGCCTCGCGGACACGACCGAC
CAGATGCTTCTTCGAAAGTTTGACGTTACTGCGGATATCCATCGTTGCGAATGGCGGATGCTGATGGATGAAAGCAAGGT
GCCGGCAACCCACCACCTGCGCGAACGTCTGATTGCATCGCGATATCATGGCGCGATCTATCCATCTTTCATGTCGCTCG
GCGGCACATGCGTCGCGCTGTGGGAATGGAATATGCCGGGTGCACCGGAGCTTCGCGCAATCGATCCAGAGGGTCGACTG
CCCAAATCACCGGCCTCCTGGTTGTAG
Antitoxin
Download Length: 78 a.a. Molecular weight: 9212.31 Da Isoelectric Point: 4.6044
>AT149618 WP_003503188.1 NZ_CP048564:c399314-399081 [Agrobacterium tumefaciens]
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEATRQRIANKERTYTLEEVMRDLDLEN
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEATRQRIANKERTYTLEEVMRDLDLEN
Download Length: 234 bp
>AT149618 NZ_CP064188:1073681-1074052 [Rhizobium sp. 007]
ATGGCAGCCACAGGCCTCAGCAATGTCGCTGCACGCTTCGGCGATGAACATTCGTCGTTTCTATCGGCCCGGCGCGTCGC
CGAGCAACTGGGCGTAACGCTCTCCGAGCTAGCCCGGCTGATCGGGGTTGCGCGCAATACGCTGGCGGCGAAATCGGGCG
CCCGCAAAGTGGATAATGCGCTGAGCAACGTCGTCCGCATCCTTGCGATGGCAAGCGAAATGGCCGGCGACGAAAACCGT
GCGGTCATATGGTTCAAGCATCAGCCGATCCCCGGTTGGGGCGGCAAGACGGCGTTTGACCTTGTCGGCGAAGGCAAGTC
CGACCGGGTTCTCGCCTATCTCGAGGCCGTCCGCTCCGGCGTCTATGCCTGA
ATGGCAGCCACAGGCCTCAGCAATGTCGCTGCACGCTTCGGCGATGAACATTCGTCGTTTCTATCGGCCCGGCGCGTCGC
CGAGCAACTGGGCGTAACGCTCTCCGAGCTAGCCCGGCTGATCGGGGTTGCGCGCAATACGCTGGCGGCGAAATCGGGCG
CCCGCAAAGTGGATAATGCGCTGAGCAACGTCGTCCGCATCCTTGCGATGGCAAGCGAAATGGCCGGCGACGAAAACCGT
GCGGTCATATGGTTCAAGCATCAGCCGATCCCCGGTTGGGGCGGCAAGACGGCGTTTGACCTTGTCGGCGAAGGCAAGTC
CGACCGGGTTCTCGCCTATCTCGAGGCCGTCCGCTCCGGCGTCTATGCCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|