Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 31989..32659 Replicon plasmid pAt1
Accession NZ_CP048560
Organism Agrobacterium fabrum strain Kin001

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FY134_RS23330 Protein ID WP_121652003.1
Coordinates 32240..32659 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FY134_RS23325 Protein ID WP_121652040.1
Coordinates 31989..32243 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FY134_RS23300 27743..28027 + 285 WP_262519075.1 DUF6527 family protein -
FY134_RS23305 (FY134_23170) 28098..28427 + 330 WP_111808238.1 hypothetical protein -
FY134_RS23310 (FY134_23175) 28501..29454 + 954 WP_111808236.1 hypothetical protein -
FY134_RS23315 (FY134_23180) 29451..30056 + 606 WP_111808272.1 dCTP deaminase -
FY134_RS23320 (FY134_23185) 30161..31777 + 1617 WP_262519055.1 SIR2 family protein -
FY134_RS23325 (FY134_23190) 31989..32243 + 255 WP_121652040.1 plasmid stabilization protein Antitoxin
FY134_RS23330 (FY134_23195) 32240..32659 + 420 WP_121652003.1 type II toxin-antitoxin system VapC family toxin Toxin
FY134_RS23335 (FY134_23200) 32950..34311 - 1362 WP_262519056.1 MATE family efflux transporter -
FY134_RS23340 (FY134_23205) 34811..35737 - 927 WP_080814654.1 LysR family transcriptional regulator -
FY134_RS23345 (FY134_23210) 35950..37302 + 1353 WP_080814653.1 MATE family efflux transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..343831 343831


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15090.35 Da        Isoelectric Point: 5.1239

>T149617 WP_121652003.1 NZ_CP048560:32240-32659 [Agrobacterium fabrum]
MILLDTNVISEPWKPVPDEAVIAWLDAQVLETLFISSITIAELRFGIAAMPFGKRQTTLRDRLEGEVLPHFSQRILSFDL
ATSQFYSDLMAHARVSGKAIGTADGYIAATAAANGLAIATRDTSPFEAAGLKVINPWSK

Download         Length: 420 bp

>T149617 NZ_CP064188:361397-361894 [Rhizobium sp. 007]
GTGACCCTCAGCGCACCGACACCACTGGCCGACCATCACGAACTGGCGGAATTCATTTCCGGCGTCGTTGAACTGGACGA
TTGGCTGCGTCGCCGCGCCCGCGCCAATCAGGCAGGCGGCGCATCGCGCACATTCGTCGTGTGCGAGGGCAACCGCGTGA
TCGCCTATTATGCGCTTGCCTCCGGCGCCGTTAAGCAGCCGGAAGCACCTGGCCGTTTCCGACGCAACATGCCCGACCCG
ATTCCGGTTGCCGTTCTCGGCCGCCTCGCCATCGACCGGACCTTTCAGGGGCGCGGTCTCGGCAGGGCATTGGTGCGCGA
TGCGGGCCTGCGTCTGCTCAATGCCGCTGAAATCCTCGGTATCCGCGGCGTGCTGGTACATGCGATTTCCGATGATGCGC
GAGCCTTCTACGAGGCAGTCGGTTTTCTGCCTTCGCCGTCCGACCCCATGATGCTGATGGTTGGGCTGCGTGATTTGAAC
AACGCGCTCAATCCTTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9331.51 Da        Isoelectric Point: 6.2300

>AT149617 WP_121652040.1 NZ_CP048560:31989-32243 [Agrobacterium fabrum]
MPAVTIRNLSDETHRALRVRAAHHGRSTEAEIRDIIEAAVRPPERIKLGSLLTAIGRDAELSESDVEALQRSRDKTAAEP
MTFE

Download         Length: 255 bp

>AT149617 NZ_CP064188:361104-361400 [Rhizobium sp. 007]
ATGCCCACATCCCACACCAGTAAAAGCGCAGATGCCAGCGTGCCGCTGAATATCCGCATCAAGCCGGCGACCCGAAACCT
TATCGATCGCGCCGCCGAGCTGCTTGGCAAGACGCGCACGGATTTCATGCTGGAGGCTTCCGAGCGCCGCGCCGAGGAAG
TTCTGCTCGACCGTACGATATTCACGGTTAGTCCCGAACTCTATGCCGAGTACCTTGCCCGGCTCGATGCGCCCGCGCAA
CCCAATGAGCGACTGAAACGTACTATGACGACCAAGGCGCCGTGGGATGAGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References